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Diagnosis, Symptoms, and Outcomes of Hirschsprung's Disease from the Perspective of Gender

Granéli, Christina LU ; Dahlin, Eero; Börjesson, Anna LU ; Arnbjörnsson, Einar LU and Stenström, Pernilla LU (2017) In Surgery research and practice 2017.
Abstract

Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9... (More)

Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9 girls were older than 4 years and participated in the BFS interview. Boys had a higher frequency of hospitalizations during the first postoperative year compared to girls (n = 20 and n = 2, p < 0.05). At long-term follow-up, more boys reported abnormal frequency of defecation, 16 compared to 2 (p < 0.05). There was no difference between genders in terms of preoperative symptoms and overall bowel function later. Conclusion. Boys with HD had more hospitalizations and a higher rate of abnormal frequency of defecation than girls with HD.

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publication status
published
subject
in
Surgery research and practice
volume
2017
pages
8 pages
publisher
Hindawi Publishing Corporation
ISSN
2356-7759
DOI
10.1155/2017/9274940
language
English
LU publication?
yes
id
caf2f5d5-2f64-45b0-a79f-99ae4064d8f8
date added to LUP
2017-06-14 09:56:51
date last changed
2017-06-14 09:56:51
@article{caf2f5d5-2f64-45b0-a79f-99ae4064d8f8,
  abstract     = {<p>Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9 girls were older than 4 years and participated in the BFS interview. Boys had a higher frequency of hospitalizations during the first postoperative year compared to girls (n = 20 and n = 2, p &lt; 0.05). At long-term follow-up, more boys reported abnormal frequency of defecation, 16 compared to 2 (p &lt; 0.05). There was no difference between genders in terms of preoperative symptoms and overall bowel function later. Conclusion. Boys with HD had more hospitalizations and a higher rate of abnormal frequency of defecation than girls with HD.</p>},
  articleno    = {9274940},
  author       = {Granéli, Christina and Dahlin, Eero and Börjesson, Anna and Arnbjörnsson, Einar and Stenström, Pernilla},
  issn         = {2356-7759},
  language     = {eng},
  pages        = {8},
  publisher    = {Hindawi Publishing Corporation},
  series       = {Surgery research and practice},
  title        = {Diagnosis, Symptoms, and Outcomes of Hirschsprung's Disease from the Perspective of Gender},
  url          = {http://dx.doi.org/10.1155/2017/9274940},
  volume       = {2017},
  year         = {2017},
}