Diagnosis, Symptoms, and Outcomes of Hirschsprung's Disease from the Perspective of Gender
(2017) In Surgery research and practice 2017.- Abstract
Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9... (More)
Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9 girls were older than 4 years and participated in the BFS interview. Boys had a higher frequency of hospitalizations during the first postoperative year compared to girls (n = 20 and n = 2, p < 0.05). At long-term follow-up, more boys reported abnormal frequency of defecation, 16 compared to 2 (p < 0.05). There was no difference between genders in terms of preoperative symptoms and overall bowel function later. Conclusion. Boys with HD had more hospitalizations and a higher rate of abnormal frequency of defecation than girls with HD.
(Less)
- author
- Granéli, Christina LU ; Dahlin, Eero ; Börjesson, Anna LU ; Arnbjörnsson, Einar LU and Stenström, Pernilla LU
- organization
- publishing date
- 2017
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Surgery research and practice
- volume
- 2017
- article number
- 9274940
- pages
- 8 pages
- publisher
- Hindawi Limited
- external identifiers
-
- pmid:28367493
- ISSN
- 2356-7759
- DOI
- 10.1155/2017/9274940
- language
- English
- LU publication?
- yes
- id
- caf2f5d5-2f64-45b0-a79f-99ae4064d8f8
- date added to LUP
- 2017-06-14 09:56:51
- date last changed
- 2018-11-21 21:32:45
@article{caf2f5d5-2f64-45b0-a79f-99ae4064d8f8, abstract = {{<p>Background/Aim. Hirschsprung's disease (HD) has a skewed gender distribution, with a female to male ratio of 1 : 4. This study aims to examine differences between boys and girls with HD regarding preoperative features and postoperative treatment and outcome. Method. The first part of the study was conducted as a retrospective review of all HD patients who underwent transanal endorectal pull-through (TERPT). Pre-, peri-, immediate post-, and first-year postoperative data were collected. The second part was conducted as an observational cross-sectional study by comparing bowel function scores (BFS) determined by structured interviews of patients 4 years old and older. Results. Included were 39 boys and 12 girls. Of these, 25 boys and 9 girls were older than 4 years and participated in the BFS interview. Boys had a higher frequency of hospitalizations during the first postoperative year compared to girls (n = 20 and n = 2, p < 0.05). At long-term follow-up, more boys reported abnormal frequency of defecation, 16 compared to 2 (p < 0.05). There was no difference between genders in terms of preoperative symptoms and overall bowel function later. Conclusion. Boys with HD had more hospitalizations and a higher rate of abnormal frequency of defecation than girls with HD.</p>}}, author = {{Granéli, Christina and Dahlin, Eero and Börjesson, Anna and Arnbjörnsson, Einar and Stenström, Pernilla}}, issn = {{2356-7759}}, language = {{eng}}, publisher = {{Hindawi Limited}}, series = {{Surgery research and practice}}, title = {{Diagnosis, Symptoms, and Outcomes of Hirschsprung's Disease from the Perspective of Gender}}, url = {{http://dx.doi.org/10.1155/2017/9274940}}, doi = {{10.1155/2017/9274940}}, volume = {{2017}}, year = {{2017}}, }