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Intra-Operative Onychoscopy of Subungual Epidermoid Inclusions

Theodosiou, Grigorios LU orcid ; Schalock, Peter C. and Svensson, Åke LU (2025) In Journal of Dermatology 52(8). p.1314-1316
Abstract

Subungual epidermoid inclusions (SEI) are small epithelial inclusions, sometimes solid but mostly with central keratinization of the onycholemmal type without a granular layer. Exceptionally, they become large enough to produce symptoms such as pain or swelling of the nail bed, resulting in subungual keratosis, onycholysis, or a dystrophic nail plate. Herein, we report a further case of SEI in a female patient with onychodystrophy of the great toe nail and highlight the onychoscopic features of SEI. Intra-operative onychoscopy facilitates the detection of SEI during a nail bed biopsy and reduces the risk of obtaining inadequate specimens for histopathologic examination.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
dermoscopy, intraoperative onychoscopy, nail disorders, nail surgery, onychoscopy, subungual onycholemmal cysts
in
Journal of Dermatology
volume
52
issue
8
pages
3 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:105007925021
  • pmid:40511888
ISSN
0385-2407
DOI
10.1111/1346-8138.17825
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2025 The Author(s). The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association.
id
cb25d869-24d7-429d-acfc-d3a5337c56d4
date added to LUP
2025-11-26 14:06:15
date last changed
2025-11-27 03:27:43
@article{cb25d869-24d7-429d-acfc-d3a5337c56d4,
  abstract     = {{<p>Subungual epidermoid inclusions (SEI) are small epithelial inclusions, sometimes solid but mostly with central keratinization of the onycholemmal type without a granular layer. Exceptionally, they become large enough to produce symptoms such as pain or swelling of the nail bed, resulting in subungual keratosis, onycholysis, or a dystrophic nail plate. Herein, we report a further case of SEI in a female patient with onychodystrophy of the great toe nail and highlight the onychoscopic features of SEI. Intra-operative onychoscopy facilitates the detection of SEI during a nail bed biopsy and reduces the risk of obtaining inadequate specimens for histopathologic examination.</p>}},
  author       = {{Theodosiou, Grigorios and Schalock, Peter C. and Svensson, Åke}},
  issn         = {{0385-2407}},
  keywords     = {{dermoscopy; intraoperative onychoscopy; nail disorders; nail surgery; onychoscopy; subungual onycholemmal cysts}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1314--1316}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Journal of Dermatology}},
  title        = {{Intra-Operative Onychoscopy of Subungual Epidermoid Inclusions}},
  url          = {{http://dx.doi.org/10.1111/1346-8138.17825}},
  doi          = {{10.1111/1346-8138.17825}},
  volume       = {{52}},
  year         = {{2025}},
}