Prevalence and incidence of non-gout crystal arthropathy in southern Sweden
Hameed, Mohaned LU ; Turkiewicz, Aleksandra LU ; Englund, Martin LU
; Jacobsson, Lennart
LU
and Kapetanovic, Meliha C.
LU
(2019)
In Arthritis Research and Therapy
21(1).
- Abstract
Objective: To estimate the prevalence and incidence of non-gout crystal arthropathy in relation to socioeconomic factors in southern Sweden. Methods: All patients (age ≥ 18 years) with at least one visit to a physician with the diagnosis of interest in the Skåne region (population of 1.3 million) in 1998-2014 were identified. Non-gout crystal arthropathy (ICD-10 codes M11.0-M11.9) was subclassified in four different groups: Calcium pyrophosphate crystal deposition related arthropathy (CPPD), unspecified non-gout arthropathies, chondrocalcinosis, and hydroxyapatite crystal deposition disease. The crude and age-adjusted point prevalence on December 31, 2014, and the cumulative incidence during 2014 were calculated for all non-gout crystal... (More)
Objective: To estimate the prevalence and incidence of non-gout crystal arthropathy in relation to socioeconomic factors in southern Sweden. Methods: All patients (age ≥ 18 years) with at least one visit to a physician with the diagnosis of interest in the Skåne region (population of 1.3 million) in 1998-2014 were identified. Non-gout crystal arthropathy (ICD-10 codes M11.0-M11.9) was subclassified in four different groups: Calcium pyrophosphate crystal deposition related arthropathy (CPPD), unspecified non-gout arthropathies, chondrocalcinosis, and hydroxyapatite crystal deposition disease. The crude and age-adjusted point prevalence on December 31, 2014, and the cumulative incidence during 2014 were calculated for all non-gout crystal arthropathies, CPPD, and other unspecified non-gout arthropathies overall and in relation to occupation, income, and level of education. Results: The crude 2014 point prevalence (95% CI) and 2014 cumulative incidence (95% CI) of all non-gout crystal arthropathies were 0.23% (0.23-0.24) and 21.5 (19-25) cases/100,000 persons. Mean age (range) among all prevalent cases in 2014 was 71 (20-102) years and 56% were males. The point prevalence and cumulative incidence of CPPD were 0.09% (0.08-0.09) and 8 (7-10)/100,000 persons, respectively. The corresponding data for unspecified non-gout crystal deposition disease was 0.16% (0.16-0.17) and 15.6 (13-18)/100,000 persons, respectively. The prevalence and incidence of CPPD and unspecified non-gout crystal arthropathies were slightly higher in men and increased with age irrespective of gender. Unspecified non-gout crystal arthropathy but not CPPD was less prevalent in persons with ≥ 15 years of education, whereas there were no clear associations with occupation and income. Conclusion: The prevalence of all diagnosed non-gout crystal arthropathies was 0.23%, thus considerably less prevalent than gout in southern Sweden. CPPD and other unspecified non-gout crystal arthropathies are the predominant diagnoses, increasing with age and in men. With the exception for unspecified non-gout crystal arthropathies being inversely correlated to a higher level of education, no convincing association with the socioeconomic factors was found.
(Less)
- author
- Hameed, Mohaned
LU
; Turkiewicz, Aleksandra
LU
; Englund, Martin
LU
; Jacobsson, Lennart
LU
and Kapetanovic, Meliha C.
LU
- organization
- publishing date
- 2019-12-17
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Calcium pyrophosphate crystal deposition disease (CPPD), Incidence, Non-gout crystal arthropathy, Prevalence, Unspecified non-gout crystal deposition disease
- in
- Arthritis Research and Therapy
- volume
- 21
- issue
- 1
- article number
- 291
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:31847885
- scopus:85076828810
- ISSN
- 1478-6354
- DOI
- 10.1186/s13075-019-2077-6
- language
- English
- LU publication?
- yes
- id
- cb66066b-e04a-446b-b802-0dcedd05d08c
- date added to LUP
- 2020-01-03 12:31:11
- date last changed
- 2024-05-02 02:44:22
@article{cb66066b-e04a-446b-b802-0dcedd05d08c,
abstract = {{<p>Objective: To estimate the prevalence and incidence of non-gout crystal arthropathy in relation to socioeconomic factors in southern Sweden. Methods: All patients (age ≥ 18 years) with at least one visit to a physician with the diagnosis of interest in the Skåne region (population of 1.3 million) in 1998-2014 were identified. Non-gout crystal arthropathy (ICD-10 codes M11.0-M11.9) was subclassified in four different groups: Calcium pyrophosphate crystal deposition related arthropathy (CPPD), unspecified non-gout arthropathies, chondrocalcinosis, and hydroxyapatite crystal deposition disease. The crude and age-adjusted point prevalence on December 31, 2014, and the cumulative incidence during 2014 were calculated for all non-gout crystal arthropathies, CPPD, and other unspecified non-gout arthropathies overall and in relation to occupation, income, and level of education. Results: The crude 2014 point prevalence (95% CI) and 2014 cumulative incidence (95% CI) of all non-gout crystal arthropathies were 0.23% (0.23-0.24) and 21.5 (19-25) cases/100,000 persons. Mean age (range) among all prevalent cases in 2014 was 71 (20-102) years and 56% were males. The point prevalence and cumulative incidence of CPPD were 0.09% (0.08-0.09) and 8 (7-10)/100,000 persons, respectively. The corresponding data for unspecified non-gout crystal deposition disease was 0.16% (0.16-0.17) and 15.6 (13-18)/100,000 persons, respectively. The prevalence and incidence of CPPD and unspecified non-gout crystal arthropathies were slightly higher in men and increased with age irrespective of gender. Unspecified non-gout crystal arthropathy but not CPPD was less prevalent in persons with ≥ 15 years of education, whereas there were no clear associations with occupation and income. Conclusion: The prevalence of all diagnosed non-gout crystal arthropathies was 0.23%, thus considerably less prevalent than gout in southern Sweden. CPPD and other unspecified non-gout crystal arthropathies are the predominant diagnoses, increasing with age and in men. With the exception for unspecified non-gout crystal arthropathies being inversely correlated to a higher level of education, no convincing association with the socioeconomic factors was found.</p>}},
author = {{Hameed, Mohaned and Turkiewicz, Aleksandra and Englund, Martin and Jacobsson, Lennart and Kapetanovic, Meliha C.}},
issn = {{1478-6354}},
keywords = {{Calcium pyrophosphate crystal deposition disease (CPPD); Incidence; Non-gout crystal arthropathy; Prevalence; Unspecified non-gout crystal deposition disease}},
language = {{eng}},
month = {{12}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{Arthritis Research and Therapy}},
title = {{Prevalence and incidence of non-gout crystal arthropathy in southern Sweden}},
url = {{http://dx.doi.org/10.1186/s13075-019-2077-6}},
doi = {{10.1186/s13075-019-2077-6}},
volume = {{21}},
year = {{2019}},
}