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Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.

Halldén, Sara LU ; Sjögren, Marketa LU ; Hedblad, Bo LU ; Engström, Gunnar LU ; Hamrefors, Viktor LU orcid ; Manjer, Jonas LU and Melander, Olle LU orcid (2016) In Journal of Internal Medicine 279(4). p.388-398
Abstract
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Internal Medicine
volume
279
issue
4
pages
388 - 398
publisher
Wiley-Blackwell
external identifiers
  • pmid:26689306
  • scopus:84961200060
  • wos:000372978800008
  • pmid:26689306
ISSN
1365-2796
DOI
10.1111/joim.12454
language
English
LU publication?
yes
id
cb7c608e-c1e5-442a-94cd-a45ea904214f (old id 8504120)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26689306?dopt=Abstract
date added to LUP
2016-04-04 09:11:21
date last changed
2024-01-12 10:12:11
@article{cb7c608e-c1e5-442a-94cd-a45ea904214f,
  abstract     = {{Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.}},
  author       = {{Halldén, Sara and Sjögren, Marketa and Hedblad, Bo and Engström, Gunnar and Hamrefors, Viktor and Manjer, Jonas and Melander, Olle}},
  issn         = {{1365-2796}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{388--398}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Journal of Internal Medicine}},
  title        = {{Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.}},
  url          = {{http://dx.doi.org/10.1111/joim.12454}},
  doi          = {{10.1111/joim.12454}},
  volume       = {{279}},
  year         = {{2016}},
}