Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Mechanism of NADH transfer among dehydrogenases

Martinez Arias, Wilma LU ; Pettersson, Henrik LU and Pettersson, Gösta LU (1998) In BBA - Protein Structure and Molecular Enzymology 1385(1). p.149-156
Abstract
Steady-state and transient-state kinetic experiments have been performed to test the proposal that there is a direct (channelled) transfer of NADH from one dehydrogenase to another if the two enzymes exhibit distinct chiral coenzyme specificity (A-side vs. B-side). The results lend no support to this proposal, but are fully consistent with a free-diffusion mechanism of NADH transfer irrespective of the chiral specificity of the enzymes.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dehydrogenase, Channelling, Enzyme kinetics
in
BBA - Protein Structure and Molecular Enzymology
volume
1385
issue
1
pages
149 - 156
publisher
Elsevier
external identifiers
  • scopus:0031807288
ISSN
0167-4838
DOI
10.1016/S0167-4838(98)00035-1
language
English
LU publication?
yes
id
cb895932-5e7f-4d28-aff8-40d5ba9249e4 (old id 125567)
alternative location
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T21-3T1BX85-J&_user=745831&_coverDate=06%2F11%2F1998&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000041498&_version=1&_urlVersion=0&_userid=745831&md5=24580464b263977f32200263048dd1ff&searchtype=a
date added to LUP
2016-04-01 16:04:44
date last changed
2022-01-28 17:06:21
@article{cb895932-5e7f-4d28-aff8-40d5ba9249e4,
  abstract     = {{Steady-state and transient-state kinetic experiments have been performed to test the proposal that there is a direct (channelled) transfer of NADH from one dehydrogenase to another if the two enzymes exhibit distinct chiral coenzyme specificity (A-side vs. B-side). The results lend no support to this proposal, but are fully consistent with a free-diffusion mechanism of NADH transfer irrespective of the chiral specificity of the enzymes.}},
  author       = {{Martinez Arias, Wilma and Pettersson, Henrik and Pettersson, Gösta}},
  issn         = {{0167-4838}},
  keywords     = {{Dehydrogenase; Channelling; Enzyme kinetics}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{149--156}},
  publisher    = {{Elsevier}},
  series       = {{BBA - Protein Structure and Molecular Enzymology}},
  title        = {{Mechanism of NADH transfer among dehydrogenases}},
  url          = {{http://dx.doi.org/10.1016/S0167-4838(98)00035-1}},
  doi          = {{10.1016/S0167-4838(98)00035-1}},
  volume       = {{1385}},
  year         = {{1998}},
}