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ABC om Syra–bastolkning på akuten

Olsson de Capretz, Pontus LU ; Lindeman, Erik and Dryver, Eric LU (2021) In Lakartidningen 118.
Abstract

The analysis of acid-base disturbances contributes to the diagnostic work-up of critically ill patients. Most emergency departments are equipped with blood gas point-of-care analyzers that quantify within minutes pH, pCO2, standard bicarbonate, standard base excess, sodium and chloride levels. This article provides a pragmatic stepwise approach to the analysis of acid-base disturbances in the emergency department. Standard base excess is used to assess the adequacy of the secondary (compensatory) response. Calculation of the anion gap based on the actual bicarbonate is used to identify the coexistence of metabolic acidosis and metabolic alkalosis. The delta anion gap allows for the identification of measurement errors, such as falsely... (More)

The analysis of acid-base disturbances contributes to the diagnostic work-up of critically ill patients. Most emergency departments are equipped with blood gas point-of-care analyzers that quantify within minutes pH, pCO2, standard bicarbonate, standard base excess, sodium and chloride levels. This article provides a pragmatic stepwise approach to the analysis of acid-base disturbances in the emergency department. Standard base excess is used to assess the adequacy of the secondary (compensatory) response. Calculation of the anion gap based on the actual bicarbonate is used to identify the coexistence of metabolic acidosis and metabolic alkalosis. The delta anion gap allows for the identification of measurement errors, such as falsely elevated lactate and chloride values, which in turn may provide diagnostic clues.

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Please use this url to cite or link to this publication:
author
; and
alternative title
Analysis of acid-base disturbances in the emergency department
publishing date
type
Contribution to journal
publication status
published
subject
in
Lakartidningen
volume
118
publisher
Swedish Medical Association
external identifiers
  • scopus:85122276520
  • pmid:34826329
ISSN
0023-7205
language
Swedish
LU publication?
no
id
cbd41d85-b9f5-491d-98d0-ea204dafed7b
alternative location
https://lakartidningen.se/klinik-och-vetenskap-1/medicinens-abc/2021/11/abc-om-syra-bastolkning-pa-akuten/
date added to LUP
2022-02-21 10:37:11
date last changed
2024-05-30 10:10:30
@article{cbd41d85-b9f5-491d-98d0-ea204dafed7b,
  abstract     = {{<p>The analysis of acid-base disturbances contributes to the diagnostic work-up of critically ill patients. Most emergency departments are equipped with blood gas point-of-care analyzers that quantify within minutes pH, pCO2, standard bicarbonate, standard base excess, sodium and chloride levels. This article provides a pragmatic stepwise approach to the analysis of acid-base disturbances in the emergency department. Standard base excess is used to assess the adequacy of the secondary (compensatory) response. Calculation of the anion gap based on the actual bicarbonate is used to identify the coexistence of metabolic acidosis and metabolic alkalosis. The delta anion gap allows for the identification of measurement errors, such as falsely elevated lactate and chloride values, which in turn may provide diagnostic clues.</p>}},
  author       = {{Olsson de Capretz, Pontus and Lindeman, Erik and Dryver, Eric}},
  issn         = {{0023-7205}},
  language     = {{swe}},
  month        = {{11}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{ABC om Syra–bastolkning på akuten}},
  url          = {{https://lakartidningen.se/klinik-och-vetenskap-1/medicinens-abc/2021/11/abc-om-syra-bastolkning-pa-akuten/}},
  volume       = {{118}},
  year         = {{2021}},
}