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Understanding Post-Sepsis Syndrome : How Can Clinicians Help?

van der Slikke, Elisabeth C. ; Beumeler, Lise F.E. ; Bouma, Hjalmar R. ; Holmqvist, Madlene LU ; Linder, Adam LU and Mankowski, Robert T. (2023) In Infection and Drug Resistance 16. p.6493-6511
Abstract

Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of “post-sepsis syndrome” (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health-and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS... (More)

Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of “post-sepsis syndrome” (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health-and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS symptoms and causative factors is vital for developing optimal care for sepsis survivors, a task of prime importance for clinicians. This review aims to elucidate our current knowledge of PSS and its relevance in enhancing post-sepsis care provided by clinicians.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
long-term outcome, post-sepsis syndrome, sepsis
in
Infection and Drug Resistance
volume
16
pages
19 pages
publisher
Dove Medical Press Ltd.
external identifiers
  • pmid:37795206
  • scopus:85173981660
ISSN
1178-6973
DOI
10.2147/IDR.S390947
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2023 van der Slikke et al.
id
cd7ae8ce-aae1-4d6e-9ef9-91f077b1e5a4
date added to LUP
2023-12-20 11:48:48
date last changed
2025-10-19 10:09:41
@article{cd7ae8ce-aae1-4d6e-9ef9-91f077b1e5a4,
  abstract     = {{<p>Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of “post-sepsis syndrome” (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health-and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS symptoms and causative factors is vital for developing optimal care for sepsis survivors, a task of prime importance for clinicians. This review aims to elucidate our current knowledge of PSS and its relevance in enhancing post-sepsis care provided by clinicians.</p>}},
  author       = {{van der Slikke, Elisabeth C. and Beumeler, Lise F.E. and Bouma, Hjalmar R. and Holmqvist, Madlene and Linder, Adam and Mankowski, Robert T.}},
  issn         = {{1178-6973}},
  keywords     = {{long-term outcome; post-sepsis syndrome; sepsis}},
  language     = {{eng}},
  pages        = {{6493--6511}},
  publisher    = {{Dove Medical Press Ltd.}},
  series       = {{Infection and Drug Resistance}},
  title        = {{Understanding Post-Sepsis Syndrome : How Can Clinicians Help?}},
  url          = {{http://dx.doi.org/10.2147/IDR.S390947}},
  doi          = {{10.2147/IDR.S390947}},
  volume       = {{16}},
  year         = {{2023}},
}