Advanced

In situ saphenous vein bypass grafting - still first line treatment? : A prospective study comparing surgical results between diabetic and non-diabetic populations

Fransson, T LU and Thörne, J LU (2010) In Vasa - European Journal of Vascular Medicine 39(1). p.59-65
Abstract

BACKGROUND: This prospective study compares results of infrainguinal revascularisation with autologous vein in diabetic and non-diabetic populations.

PATIENTS AND METHODS: 101 patients (diabetics (A) n = 50 and non-diabetics (B) n = 51) were operated upon with an in situ saphenous vein bypass to the popliteal artery below knee or to crural arteries, due to critical ischemia. Data on operative details, morbidity, mortality, secondary interventions and graft patency, were collected prospectively. All patients were followed up for 5 years.

RESULTS: The two groups were similar except that diabetics more often suffered from gangrene or tissue loss. The distal anastomoses were constructed significantly more distally in diabetics.... (More)

BACKGROUND: This prospective study compares results of infrainguinal revascularisation with autologous vein in diabetic and non-diabetic populations.

PATIENTS AND METHODS: 101 patients (diabetics (A) n = 50 and non-diabetics (B) n = 51) were operated upon with an in situ saphenous vein bypass to the popliteal artery below knee or to crural arteries, due to critical ischemia. Data on operative details, morbidity, mortality, secondary interventions and graft patency, were collected prospectively. All patients were followed up for 5 years.

RESULTS: The two groups were similar except that diabetics more often suffered from gangrene or tissue loss. The distal anastomoses were constructed significantly more distally in diabetics. There were no differences in perioperative bleeding, length of operation, hospital stay or 30 d mortality. The 5 year patency did not differ significantly between groups, A 68 % vs. B 72 %. The limb salvage was equal in both groups, 86 % after 5 years. Mortality during follow up was significantly higher among diabetics, at two years A 31 % vs. B 14 %.

CONCLUSIONS: Distal revascularisation with in situ technique is a durable procedure that can be performed with very good results in both diabetics and non-diabetics. The survival among diabetics is however significantly lower, although reaching 69 % at two years.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aged, Diabetes Complications, Diabetic Angiopathies, Female, Follow-Up Studies, Gangrene, Humans, Ischemia, Leg, Male, Patient Selection, Popliteal Artery, Saphenous Vein, Survival Rate, Journal Article
in
Vasa - European Journal of Vascular Medicine
volume
39
issue
1
pages
59 - 65
publisher
Hans Huber
external identifiers
  • scopus:77749273834
ISSN
0301-1526
DOI
10.1024/0301-1526/a000006
language
English
LU publication?
yes
id
ce8b3a04-b239-498e-b3c6-25e509727544
date added to LUP
2017-04-06 10:01:21
date last changed
2018-07-01 04:44:32
@article{ce8b3a04-b239-498e-b3c6-25e509727544,
  abstract     = {<p>BACKGROUND: This prospective study compares results of infrainguinal revascularisation with autologous vein in diabetic and non-diabetic populations.</p><p>PATIENTS AND METHODS: 101 patients (diabetics (A) n = 50 and non-diabetics (B) n = 51) were operated upon with an in situ saphenous vein bypass to the popliteal artery below knee or to crural arteries, due to critical ischemia. Data on operative details, morbidity, mortality, secondary interventions and graft patency, were collected prospectively. All patients were followed up for 5 years.</p><p>RESULTS: The two groups were similar except that diabetics more often suffered from gangrene or tissue loss. The distal anastomoses were constructed significantly more distally in diabetics. There were no differences in perioperative bleeding, length of operation, hospital stay or 30 d mortality. The 5 year patency did not differ significantly between groups, A 68 % vs. B 72 %. The limb salvage was equal in both groups, 86 % after 5 years. Mortality during follow up was significantly higher among diabetics, at two years A 31 % vs. B 14 %.</p><p>CONCLUSIONS: Distal revascularisation with in situ technique is a durable procedure that can be performed with very good results in both diabetics and non-diabetics. The survival among diabetics is however significantly lower, although reaching 69 % at two years.</p>},
  author       = {Fransson, T and Thörne, J},
  issn         = {0301-1526},
  keyword      = {Aged,Diabetes Complications,Diabetic Angiopathies,Female,Follow-Up Studies,Gangrene,Humans,Ischemia,Leg,Male,Patient Selection,Popliteal Artery,Saphenous Vein,Survival Rate,Journal Article},
  language     = {eng},
  number       = {1},
  pages        = {59--65},
  publisher    = {Hans Huber},
  series       = {Vasa - European Journal of Vascular Medicine},
  title        = {In situ saphenous vein bypass grafting - still first line treatment? : A prospective study comparing surgical results between diabetic and non-diabetic populations},
  url          = {http://dx.doi.org/10.1024/0301-1526/a000006},
  volume       = {39},
  year         = {2010},
}