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Immunsvar och inflammation vid Crohns sjukdom. Snart mojligt driva diagnostiken langre och utveckla mer specifika lakemedel

Lindgren, Stefan LU and Egesten, Arne LU (1999) In Läkartidningen 96(1-2). p.52-55
Abstract
The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heterogenous nature of Crohn's disease, thus enabling the disease to be subtyped and individualised therapy directed primarily at down-regulation of helper T-cell-1 response to be developed.
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Läkartidningen
volume
96
issue
1-2
pages
52 - 55
publisher
Swedish Medical Association
external identifiers
  • scopus:0033527947
ISSN
1652-7518
language
English
LU publication?
yes
id
cf11c596-afae-498c-a8ff-ef92808d3b89 (old id 1296614)
date added to LUP
2016-04-04 14:15:10
date last changed
2022-01-30 01:39:37
@article{cf11c596-afae-498c-a8ff-ef92808d3b89,
  abstract     = {{The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heterogenous nature of Crohn's disease, thus enabling the disease to be subtyped and individualised therapy directed primarily at down-regulation of helper T-cell-1 response to be developed.}},
  author       = {{Lindgren, Stefan and Egesten, Arne}},
  issn         = {{1652-7518}},
  language     = {{eng}},
  number       = {{1-2}},
  pages        = {{52--55}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Läkartidningen}},
  title        = {{Immunsvar och inflammation vid Crohns sjukdom. Snart mojligt driva diagnostiken langre och utveckla mer specifika lakemedel}},
  volume       = {{96}},
  year         = {{1999}},
}