The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions
(2021) In Journal of Ultrasonography 21(84). p.22-33- Abstract
Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrospective analysis performed at a regional sarcoma center over one year included patients referred for ultrasound-guided biopsy of musculoskeletal soft tissue lesions. At least 6 months’ clinical and radiological follow-up, results from repeat or excisional biopsy, or interventional treatment, served as outcome reference. The biopsy procedure and... (More)
Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrospective analysis performed at a regional sarcoma center over one year included patients referred for ultrasound-guided biopsy of musculoskeletal soft tissue lesions. At least 6 months’ clinical and radiological follow-up, results from repeat or excisional biopsy, or interventional treatment, served as outcome reference. The biopsy procedure and yield were analyzed. The biopsy was classified as ‘diagnostic’ when a defini-tive diagnosis could be made on the first biopsy, and ‘accurate’ when only the malignant or benign nature of the tumor could be determined. Results: From 102 referrals for biopsy of soft tissue lesions in 2019, a total of 73 biopsies of solid lesions with a 16-gauge cutting needle were included (73 patients). There were 34 males and 39 females, with a mean age of 57.7 years. The overall proportion of diagnostic biopsies was 84%, for malignant lesions 88% and benign lesions 81%. The tumor could be classified as malignant or benign in 12 patients (16%) (accurate biopsy). It was possible to discriminate between malignant and benign lesions in each case. The majority of biopsied lesions were benign 64% (n = 47). Conclusion: The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions performed with 16-gauge needle is good, with a high rate of diagnostic biopsies, both for benign and malignant lesions.
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- author
- Szaro, Paweł ; Wong, Andrew ; Blain, Elena ; Gataa, Khaldun Ghali and Geijer, Mats LU
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Biopsy, Diagnostic biopsy, Musculoskeletal system, Solid tumor, Ultrasound
- in
- Journal of Ultrasonography
- volume
- 21
- issue
- 84
- pages
- 22 - 33
- publisher
- Polish Ultrasound Society
- external identifiers
-
- scopus:85103097724
- pmid:33791113
- ISSN
- 2084-8404
- DOI
- 10.15557/JoU.2021.0004
- language
- English
- LU publication?
- yes
- id
- cf60b06b-3920-4b0a-9b17-9fb0a10dbabc
- date added to LUP
- 2021-04-09 08:38:45
- date last changed
- 2024-06-15 09:34:33
@article{cf60b06b-3920-4b0a-9b17-9fb0a10dbabc,
abstract = {{<p>Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrospective analysis performed at a regional sarcoma center over one year included patients referred for ultrasound-guided biopsy of musculoskeletal soft tissue lesions. At least 6 months’ clinical and radiological follow-up, results from repeat or excisional biopsy, or interventional treatment, served as outcome reference. The biopsy procedure and yield were analyzed. The biopsy was classified as ‘diagnostic’ when a defini-tive diagnosis could be made on the first biopsy, and ‘accurate’ when only the malignant or benign nature of the tumor could be determined. Results: From 102 referrals for biopsy of soft tissue lesions in 2019, a total of 73 biopsies of solid lesions with a 16-gauge cutting needle were included (73 patients). There were 34 males and 39 females, with a mean age of 57.7 years. The overall proportion of diagnostic biopsies was 84%, for malignant lesions 88% and benign lesions 81%. The tumor could be classified as malignant or benign in 12 patients (16%) (accurate biopsy). It was possible to discriminate between malignant and benign lesions in each case. The majority of biopsied lesions were benign 64% (n = 47). Conclusion: The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions performed with 16-gauge needle is good, with a high rate of diagnostic biopsies, both for benign and malignant lesions.</p>}},
author = {{Szaro, Paweł and Wong, Andrew and Blain, Elena and Gataa, Khaldun Ghali and Geijer, Mats}},
issn = {{2084-8404}},
keywords = {{Biopsy; Diagnostic biopsy; Musculoskeletal system; Solid tumor; Ultrasound}},
language = {{eng}},
number = {{84}},
pages = {{22--33}},
publisher = {{Polish Ultrasound Society}},
series = {{Journal of Ultrasonography}},
title = {{The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions}},
url = {{http://dx.doi.org/10.15557/JoU.2021.0004}},
doi = {{10.15557/JoU.2021.0004}},
volume = {{21}},
year = {{2021}},
}