Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry
Sagrista, Ester ; Larsson, Estelle LU
; Ezoddin, Maryam
; Hidalgo, Manuela
; Salvado, Victoria
and Jönsson, Jan Åke
LU
(2010)
In Journal of Chromatography A
1217(40).
p.6153-6158
- Abstract
- In this study, a three-phase hollow fiber liquid-phase microextraction (HF-LPME) method combined with liquid chromatography-mass spectrometry was developed for direct determination of four non-steroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in sewage sludge. The drugs were extracted from non-spiked and spiked slurry samples with different amounts of sludge into an organic phase and then back-extracted into an aqueous phase held in the lumen of the hollow fiber. High enrichment factors ranging from 2761 to 3254 in pure water were achieved. In sludge samples, repeatability and inter-clay precision were tested with relative standard deviation values between 10-18% and 7-15%, respectively. Average... (More)
- In this study, a three-phase hollow fiber liquid-phase microextraction (HF-LPME) method combined with liquid chromatography-mass spectrometry was developed for direct determination of four non-steroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in sewage sludge. The drugs were extracted from non-spiked and spiked slurry samples with different amounts of sludge into an organic phase and then back-extracted into an aqueous phase held in the lumen of the hollow fiber. High enrichment factors ranging from 2761 to 3254 in pure water were achieved. In sludge samples, repeatability and inter-clay precision were tested with relative standard deviation values between 10-18% and 7-15%, respectively. Average concentrations of 29 +/- 9, 138 +/- 2, 39 +/- 5 and 122 +/- 7 ng/g were determined in dried sludge from Kallby sewage treatment plant (Sweden) for ketoprofen, naproxen, diclofenac and ibuprofen, respectively. (C) 2010 Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1727041
- author
- Sagrista, Ester
; Larsson, Estelle
LU
; Ezoddin, Maryam
; Hidalgo, Manuela
; Salvado, Victoria
and Jönsson, Jan Åke
LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- NSAIDs, Sewage sludge, Hollow fiber supported liquid membrane, HF-LPME
- in
- Journal of Chromatography A
- volume
- 1217
- issue
- 40
- pages
- 6153 - 6158
- publisher
- Elsevier
- external identifiers
-
- wos:000282725800004
- scopus:77956652058
- pmid:20810117
- ISSN
- 0021-9673
- DOI
- 10.1016/j.chroma.2010.08.005
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004), Department of Chemistry (011001220)
- id
- d00661c0-6ec4-4bdd-b5a4-c6ce54706b4d (old id 1727041)
- date added to LUP
- 2016-04-01 13:32:54
- date last changed
- 2025-04-04 15:16:20
@article{d00661c0-6ec4-4bdd-b5a4-c6ce54706b4d,
abstract = {{In this study, a three-phase hollow fiber liquid-phase microextraction (HF-LPME) method combined with liquid chromatography-mass spectrometry was developed for direct determination of four non-steroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in sewage sludge. The drugs were extracted from non-spiked and spiked slurry samples with different amounts of sludge into an organic phase and then back-extracted into an aqueous phase held in the lumen of the hollow fiber. High enrichment factors ranging from 2761 to 3254 in pure water were achieved. In sludge samples, repeatability and inter-clay precision were tested with relative standard deviation values between 10-18% and 7-15%, respectively. Average concentrations of 29 +/- 9, 138 +/- 2, 39 +/- 5 and 122 +/- 7 ng/g were determined in dried sludge from Kallby sewage treatment plant (Sweden) for ketoprofen, naproxen, diclofenac and ibuprofen, respectively. (C) 2010 Elsevier B.V. All rights reserved.}},
author = {{Sagrista, Ester and Larsson, Estelle and Ezoddin, Maryam and Hidalgo, Manuela and Salvado, Victoria and Jönsson, Jan Åke}},
issn = {{0021-9673}},
keywords = {{NSAIDs; Sewage sludge; Hollow fiber supported liquid membrane; HF-LPME}},
language = {{eng}},
number = {{40}},
pages = {{6153--6158}},
publisher = {{Elsevier}},
series = {{Journal of Chromatography A}},
title = {{Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry}},
url = {{http://dx.doi.org/10.1016/j.chroma.2010.08.005}},
doi = {{10.1016/j.chroma.2010.08.005}},
volume = {{1217}},
year = {{2010}},
}