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Comparison of the Accuracy of the Novel PrisMax Continuous Renal Replacement Therapy System to the Classic Prismaflex System

Bell, Max ; Broman, Marcus LU ; Joannes-Boyau, Olivier and Ronco, Claudio (2018) In Blood Purification
Abstract

Background/Aims: We assessed how the novel PrisMax continuous renal replacement therapy (CRRT) system performed in an international multicentre setting. The system has multiple novel tools aiming to increase accuracy and dose delivery. Methods: Data was prospectively collected from 7 intensive care units in 6 countries. The PrisMax device data logs constituted the raw material and last generation Prismaflex data was used as comparison. Clinical parameters like treatment time, filter life span, downtime as well as prescribed and delivered dose were recorded. Results: PrisMax delivered/prescribed effluent ratios (mean ± SD) 0.92 ± 0.15 vs. Prismaflex ratios 0.85 ± 0.21, p < 0.001; delivered effluent dose (mL/kg/h) was 18.16 ± 12.93 vs.... (More)

Background/Aims: We assessed how the novel PrisMax continuous renal replacement therapy (CRRT) system performed in an international multicentre setting. The system has multiple novel tools aiming to increase accuracy and dose delivery. Methods: Data was prospectively collected from 7 intensive care units in 6 countries. The PrisMax device data logs constituted the raw material and last generation Prismaflex data was used as comparison. Clinical parameters like treatment time, filter life span, downtime as well as prescribed and delivered dose were recorded. Results: PrisMax delivered/prescribed effluent ratios (mean ± SD) 0.92 ± 0.15 vs. Prismaflex ratios 0.85 ± 0.21, p < 0.001; delivered effluent dose (mL/kg/h) was 18.16 ± 12.93 vs. 10.95 ± 10.96, p < 0.0001; and (Kt/V) 0.76 ± 0.52 vs. 0.44 ± 0.44, p < 0.0001. Moreover, downtime was 27 minutes less for the newer device. Conclusion: The PrisMax CRRT device outperforms its predecessor with regard to dose delivery and accuracy.

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author
; ; and
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Acute kidney injury, Citrate, Continuous hemodiafiltration, Critical care, Dialysis efficiency, Dialysis machine, Hemodiafiltration
in
Blood Purification
pages
5 pages
publisher
Karger
external identifiers
  • pmid:30428467
  • scopus:85056892143
ISSN
0253-5068
DOI
10.1159/000494764
language
English
LU publication?
no
id
d066ef84-fc83-45a3-8dfa-af6b11a05366
date added to LUP
2018-11-30 09:17:06
date last changed
2020-10-20 01:54:37
@article{d066ef84-fc83-45a3-8dfa-af6b11a05366,
  abstract     = {<p>Background/Aims: We assessed how the novel PrisMax continuous renal replacement therapy (CRRT) system performed in an international multicentre setting. The system has multiple novel tools aiming to increase accuracy and dose delivery. Methods: Data was prospectively collected from 7 intensive care units in 6 countries. The PrisMax device data logs constituted the raw material and last generation Prismaflex data was used as comparison. Clinical parameters like treatment time, filter life span, downtime as well as prescribed and delivered dose were recorded. Results: PrisMax delivered/prescribed effluent ratios (mean ± SD) 0.92 ± 0.15 vs. Prismaflex ratios 0.85 ± 0.21, p &lt; 0.001; delivered effluent dose (mL/kg/h) was 18.16 ± 12.93 vs. 10.95 ± 10.96, p &lt; 0.0001; and (Kt/V) 0.76 ± 0.52 vs. 0.44 ± 0.44, p &lt; 0.0001. Moreover, downtime was 27 minutes less for the newer device. Conclusion: The PrisMax CRRT device outperforms its predecessor with regard to dose delivery and accuracy.</p>},
  author       = {Bell, Max and Broman, Marcus and Joannes-Boyau, Olivier and Ronco, Claudio},
  issn         = {0253-5068},
  language     = {eng},
  month        = {11},
  publisher    = {Karger},
  series       = {Blood Purification},
  title        = {Comparison of the Accuracy of the Novel PrisMax Continuous Renal Replacement Therapy System to the Classic Prismaflex System},
  url          = {http://dx.doi.org/10.1159/000494764},
  doi          = {10.1159/000494764},
  year         = {2018},
}