Advanced

Regulating Germline Editing in Assisted Reproductive Technology : An EU Cross-disciplinary Perspective

Nordberg, Ana LU ; Minssen, Timo ; Feeney, Oliver ; de Miguel Beiren, Inigo ; Galvani, Lucia and Wartiovaara, Kirmo (2020) In Bioethics 34(1). p.16-32
Abstract
Potential applications of genome editing in assisted reproductive technology (ART) raise a vast array of strong opinions, emotional reactions and divergent perceptions. Acknowledging the need for caution and respecting such reactions, we observe that at least some are based on either a misunderstanding of the science or misconceptions about the content and flexibility of the existing legal frameworks. Combining medical, legal and ethical expertise, we present and discuss regulatory responses at the national, European and international levels. The discussion has a EU starting point and is meant as a contribute to the general international regulatory debate. Overall, this paper concludes that gene editing technologies should not be regulated... (More)
Potential applications of genome editing in assisted reproductive technology (ART) raise a vast array of strong opinions, emotional reactions and divergent perceptions. Acknowledging the need for caution and respecting such reactions, we observe that at least some are based on either a misunderstanding of the science or misconceptions about the content and flexibility of the existing legal frameworks. Combining medical, legal and ethical expertise, we present and discuss regulatory responses at the national, European and international levels. The discussion has a EU starting point and is meant as a contribute to the general international regulatory debate. Overall, this paper concludes that gene editing technologies should not be regulated autonomously. Rather, potential uses should be regulated under general, existing frameworks and where applicable by reference to sufficiently equivalent technologies and techniques already subject to specific regulation. To be clear, we do not argue for the hasty introduction of gene editing as a reproductive treatment option in the immediate future. We call for caution with regard to overreaching moratoria and prohibitions which will also affect basic research. We recommend flexible regulations that allow for further responsible research into the potential development of the technology. We call for an open and inclusive debate and argue that scientific communication should claim a more prominent role to counter the danger of widespread misinformation. A high level of transparency and accuracy should guide scientific communication while simultaneously global-scale responsibility and governance should be fostered by promoting cross-disciplinary thinking and multi-level stakeholder involvement in legal and regulatory processes. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Assisted Reproduction Technology, Gene editing, Germ line modifications, Civil law, Privatr├Ątt
in
Bioethics
volume
34
issue
1
pages
16 - 32
publisher
Wiley-Blackwell
external identifiers
  • scopus:85077148213
  • pmid:31877579
ISSN
0269-9702
DOI
10.1111/bioe.12705
language
English
LU publication?
yes
id
d1277e36-f617-469b-a4f1-91961abeeb34
date added to LUP
2018-07-28 15:17:30
date last changed
2020-01-16 03:27:34
@article{d1277e36-f617-469b-a4f1-91961abeeb34,
  abstract     = {Potential applications of genome editing in assisted reproductive technology (ART) raise a vast array of strong opinions, emotional reactions and divergent perceptions. Acknowledging the need for caution and respecting such reactions, we observe that at least some are based on either a misunderstanding of the science or misconceptions about the content and flexibility of the existing legal frameworks. Combining medical, legal and ethical expertise, we present and discuss regulatory responses at the national, European and international levels. The discussion has a EU starting point and is meant as a contribute to the general international regulatory debate. Overall, this paper concludes that gene editing technologies should not be regulated autonomously. Rather, potential uses should be regulated under general, existing frameworks and where applicable by reference to sufficiently equivalent technologies and techniques already subject to specific regulation. To be clear, we do not argue for the hasty introduction of gene editing as a reproductive treatment option in the immediate future. We call for caution with regard to overreaching moratoria and prohibitions which will also affect basic research. We recommend flexible regulations that allow for further responsible research into the potential development of the technology. We call for an open and inclusive debate and argue that scientific communication should claim a more prominent role to counter the danger of widespread misinformation. A high level of transparency and accuracy should guide scientific communication while simultaneously global-scale responsibility and governance should be fostered by promoting cross-disciplinary thinking and multi-level stakeholder involvement in legal and regulatory processes. },
  author       = {Nordberg, Ana and Minssen, Timo and Feeney, Oliver and de Miguel Beiren, Inigo and Galvani, Lucia and Wartiovaara, Kirmo},
  issn         = {0269-9702},
  language     = {eng},
  number       = {1},
  pages        = {16--32},
  publisher    = {Wiley-Blackwell},
  series       = {Bioethics},
  title        = {Regulating Germline Editing in Assisted Reproductive Technology : An EU Cross-disciplinary Perspective},
  url          = {http://dx.doi.org/10.1111/bioe.12705},
  doi          = {10.1111/bioe.12705},
  volume       = {34},
  year         = {2020},
}