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The molecular clutch model for mechanotransduction evolves

Swaminathan, Vinay LU and Waterman, Clare M (2016) In Nature Cell Biology 18(5). p.61-459
Abstract

Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.

Please use this url to cite or link to this publication:
author
and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Integrins, Mechanotransduction, Cellular
in
Nature Cell Biology
volume
18
issue
5
pages
3 pages
publisher
Nature Publishing Group
external identifiers
  • pmid:27117328
  • scopus:84964658621
ISSN
1465-7392
DOI
10.1038/ncb3350
language
English
LU publication?
no
id
d1715962-fa78-429d-9990-747d567a28a2
date added to LUP
2018-09-07 16:53:00
date last changed
2024-04-15 11:11:12
@article{d1715962-fa78-429d-9990-747d567a28a2,
  abstract     = {{<p>Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.</p>}},
  author       = {{Swaminathan, Vinay and Waterman, Clare M}},
  issn         = {{1465-7392}},
  keywords     = {{Integrins; Mechanotransduction, Cellular}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{5}},
  pages        = {{61--459}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Nature Cell Biology}},
  title        = {{The molecular clutch model for mechanotransduction evolves}},
  url          = {{http://dx.doi.org/10.1038/ncb3350}},
  doi          = {{10.1038/ncb3350}},
  volume       = {{18}},
  year         = {{2016}},
}