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Injectable Functional Polymeric Cryogels for Biological Applications

Çimen, Duygu ; Özbek, Merve Asena ; Bereli, Nilay ; Mattiasson, Bo LU and Denizli, Adil (2025) In Biomedical Materials and Devices 3(1). p.288-298
Abstract

In recent years, injectable cryogels have been frequently used in various biomedical applications such as tissue engineering, drug delivery, therapeutics, therapy, cell transplantation and immunotherapy. Cryogels, one of the biomaterials with injectable 3D scaffold structures, have important properties such as biocompatibility, physical resistance, macropore and sensitivity. In addition to being biocompatible, cryogels, consisting of three-dimensional (3D) scaffolds with physicochemical properties such as elasticity, hardness and biological degradation, provide a structural support environment for tissue development along with cell attachment. In addition, injectable cryogels can be loaded with therapeutic agents or cells in tissue... (More)

In recent years, injectable cryogels have been frequently used in various biomedical applications such as tissue engineering, drug delivery, therapeutics, therapy, cell transplantation and immunotherapy. Cryogels, one of the biomaterials with injectable 3D scaffold structures, have important properties such as biocompatibility, physical resistance, macropore and sensitivity. In addition to being biocompatible, cryogels, consisting of three-dimensional (3D) scaffolds with physicochemical properties such as elasticity, hardness and biological degradation, provide a structural support environment for tissue development along with cell attachment. In addition, injectable cryogels can be loaded with therapeutic agents or cells in tissue engineering and clinical studies. The purpose of this review is to explain the physical and chemical properties of injectable cryogels consisting of three-dimensional scaffolding, after explaining the properties and synthesis stages of cryogels, and it is thought to be a guide to make their use in different areas more widespread for future studies.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biomedicine application, Cryogel, Injectable cryogel, Polymer, Supermacroporous
in
Biomedical Materials and Devices
volume
3
issue
1
article number
110234
pages
11 pages
publisher
Springer Nature
external identifiers
  • scopus:85219648077
ISSN
2731-4812
DOI
10.1007/s44174-024-00190-4
language
English
LU publication?
yes
id
d194feff-dde5-4cb9-a42d-7b2c1812ab3c
date added to LUP
2025-06-19 11:40:28
date last changed
2025-06-19 11:41:51
@article{d194feff-dde5-4cb9-a42d-7b2c1812ab3c,
  abstract     = {{<p>In recent years, injectable cryogels have been frequently used in various biomedical applications such as tissue engineering, drug delivery, therapeutics, therapy, cell transplantation and immunotherapy. Cryogels, one of the biomaterials with injectable 3D scaffold structures, have important properties such as biocompatibility, physical resistance, macropore and sensitivity. In addition to being biocompatible, cryogels, consisting of three-dimensional (3D) scaffolds with physicochemical properties such as elasticity, hardness and biological degradation, provide a structural support environment for tissue development along with cell attachment. In addition, injectable cryogels can be loaded with therapeutic agents or cells in tissue engineering and clinical studies. The purpose of this review is to explain the physical and chemical properties of injectable cryogels consisting of three-dimensional scaffolding, after explaining the properties and synthesis stages of cryogels, and it is thought to be a guide to make their use in different areas more widespread for future studies.</p>}},
  author       = {{Çimen, Duygu and Özbek, Merve Asena and Bereli, Nilay and Mattiasson, Bo and Denizli, Adil}},
  issn         = {{2731-4812}},
  keywords     = {{Biomedicine application; Cryogel; Injectable cryogel; Polymer; Supermacroporous}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{288--298}},
  publisher    = {{Springer Nature}},
  series       = {{Biomedical Materials and Devices}},
  title        = {{Injectable Functional Polymeric Cryogels for Biological Applications}},
  url          = {{http://dx.doi.org/10.1007/s44174-024-00190-4}},
  doi          = {{10.1007/s44174-024-00190-4}},
  volume       = {{3}},
  year         = {{2025}},
}