Applied in situ product recovery in ABE fermentation
Outram, Victoria LU
; Lalander, Carl-Axel
; Lee, Jonathan G. M.
; Davies, E. Timothy
and Harvey, Adam P.
(2017)
In Biotechnology Progress
33(3).
p.563-579
- Abstract
The production of biobutanol is hindered by the product's toxicity to the bacteria, which limits the productivity of the process. In situ product recovery of butanol can improve the productivity by removing the source of inhibition. This paper reviews in situ product recovery techniques applied to the acetone butanol ethanol fermentation in a stirred tank reactor. Methods of in situ recovery include gas stripping, vacuum fermentation, pervaporation, liquid–liquid extraction, perstraction, and adsorption, all of which have been investigated for the acetone, butanol, and ethanol fermentation. All techniques have shown an improvement in substrate utilization, yield, productivity or both. Different fermentation modes favored different... (More)
The production of biobutanol is hindered by the product's toxicity to the bacteria, which limits the productivity of the process. In situ product recovery of butanol can improve the productivity by removing the source of inhibition. This paper reviews in situ product recovery techniques applied to the acetone butanol ethanol fermentation in a stirred tank reactor. Methods of in situ recovery include gas stripping, vacuum fermentation, pervaporation, liquid–liquid extraction, perstraction, and adsorption, all of which have been investigated for the acetone, butanol, and ethanol fermentation. All techniques have shown an improvement in substrate utilization, yield, productivity or both. Different fermentation modes favored different techniques. For batch processing gas stripping and pervaporation were most favorable, but in fed-batch fermentations gas stripping and adsorption were most promising. During continuous processing perstraction appeared to offer the best improvement. The use of hybrid techniques can increase the final product concentration beyond that of single-stage techniques. Therefore, the selection of an in situ product recovery technique would require comparable information on the energy demand and economics of the process.
(Less)
- author
- Outram, Victoria
LU
; Lalander, Carl-Axel
; Lee, Jonathan G. M.
; Davies, E. Timothy
and Harvey, Adam P.
- publishing date
- 2017-05-01
- type
- Contribution to journal
- publication status
- published
- keywords
- ABE Fermentation, In situ product recovery, n-Butanol
- in
- Biotechnology Progress
- volume
- 33
- issue
- 3
- pages
- 17 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:28188696
- scopus:85020935966
- ISSN
- 8756-7938
- DOI
- 10.1002/btpr.2446
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © 2017 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers
- id
- d32ccb0d-8336-4a06-9be6-b1366bc3531f
- date added to LUP
- 2023-05-04 14:17:52
- date last changed
- 2024-05-18 00:49:46
@article{d32ccb0d-8336-4a06-9be6-b1366bc3531f,
abstract = {{<p>The production of biobutanol is hindered by the product's toxicity to the bacteria, which limits the productivity of the process. In situ product recovery of butanol can improve the productivity by removing the source of inhibition. This paper reviews in situ product recovery techniques applied to the acetone butanol ethanol fermentation in a stirred tank reactor. Methods of in situ recovery include gas stripping, vacuum fermentation, pervaporation, liquid–liquid extraction, perstraction, and adsorption, all of which have been investigated for the acetone, butanol, and ethanol fermentation. All techniques have shown an improvement in substrate utilization, yield, productivity or both. Different fermentation modes favored different techniques. For batch processing gas stripping and pervaporation were most favorable, but in fed-batch fermentations gas stripping and adsorption were most promising. During continuous processing perstraction appeared to offer the best improvement. The use of hybrid techniques can increase the final product concentration beyond that of single-stage techniques. Therefore, the selection of an in situ product recovery technique would require comparable information on the energy demand and economics of the process.</p>}},
author = {{Outram, Victoria and Lalander, Carl-Axel and Lee, Jonathan G. M. and Davies, E. Timothy and Harvey, Adam P.}},
issn = {{8756-7938}},
keywords = {{ABE Fermentation; In situ product recovery; n-Butanol}},
language = {{eng}},
month = {{05}},
number = {{3}},
pages = {{563--579}},
publisher = {{The American Chemical Society (ACS)}},
series = {{Biotechnology Progress}},
title = {{Applied <i>in situ </i>product recovery in ABE fermentation}},
url = {{http://dx.doi.org/10.1002/btpr.2446}},
doi = {{10.1002/btpr.2446}},
volume = {{33}},
year = {{2017}},
}