Hierarchical build-up of bio-based nanofibrous materials with tunable metal–organic framework biofunctionality
(2021) In Materials Today 48. p.47-58- Abstract
Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could replace existing inefficient drying processes. These ambient-dried aerogels (∼99% porosity) exhibit a high specific compressive modulus (26.8 ± 6.1 kPa m3 kg−1, approaching equivalence of carbon-nanotube-reinforced aerogels), wet stability and shape recovery (80–90%), favorable specific surface area (90 m2... (More)
Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could replace existing inefficient drying processes. These ambient-dried aerogels (∼99% porosity) exhibit a high specific compressive modulus (26.8 ± 6.1 kPa m3 kg−1, approaching equivalence of carbon-nanotube-reinforced aerogels), wet stability and shape recovery (80–90%), favorable specific surface area (90 m2 g−1) and tunable densities (2–20 kg m−3). The aerogels provide an ideal nanofibrillar substrate for in-situ growth of metal–organic frameworks (MOFs), via co-assembly of MOF precursors with proteins in aqueous solutions. The resulting hybrid aerogels show a nine-fold increase in surface area (810 m2g−1), with preserved wet stability and additional protein biofunctionality. The hybrid aerogels facilitate a pH-controlled release of immobilized proteins, following a concomitant disassembly of the surface grown MOFs, demonstrating their use in controlled delivery systems. The colorimetric protein binding assay of the biofunctionalized hybrid aerogel also demonstrates the potential of the material as a novel 3D bioassay platform, which could potentially be an alternative to plate-based enzyme-linked immunosorbent assay.
(Less)
- author
- Rostami, Jowan ; Gordeyeva, Korneliya ; Benselfelt, Tobias ; Lahchaichi, Ekeram ; Hall, Stephen A. LU ; Riazanova, Anastasia V. ; Larsson, Per A. ; Cinar Ciftci, Goksu and Wågberg, Lars
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 3D lightweight materials, Aerogels, Cellulose nanofibrils, Controlled release, Metal–organic frameworks, Protein binding assay
- in
- Materials Today
- volume
- 48
- pages
- 47 - 58
- publisher
- Elsevier
- external identifiers
-
- scopus:85106632112
- ISSN
- 1369-7021
- DOI
- 10.1016/j.mattod.2021.04.013
- language
- English
- LU publication?
- yes
- additional info
- Funding Information: JR acknowledges VR, the Swedish Research Council, for financial support and LW acknowledges the Knut and Alice Wallenberg Research Foundation, via WWSC, for financial support. The authors acknowledge the Treesearch organization for financial support and the facilities and technical assistance of Cheng Choo Lee at the Ume? Core Facility Electron Microscopy (UCEM), Umeå University and the National Microscopy Infrastructure (NMI). The tomography analysis (SH) was in part supported by the QIM project at Lund University. The authors would also like to thank Miscible Text for proofreading the language of the manuscript and Andrew Marais for contributing photographs. The authors declare no conflict of interest.
- id
- d336186f-ea8f-4f6f-aa82-81f9cb597b88
- date added to LUP
- 2021-06-11 11:47:29
- date last changed
- 2022-04-27 02:25:29
@article{d336186f-ea8f-4f6f-aa82-81f9cb597b88,
abstract = {{<p>Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could replace existing inefficient drying processes. These ambient-dried aerogels (∼99% porosity) exhibit a high specific compressive modulus (26.8 ± 6.1 kPa m<sup>3</sup> kg<sup>−1</sup>, approaching equivalence of carbon-nanotube-reinforced aerogels), wet stability and shape recovery (80–90%), favorable specific surface area (90 m<sup>2</sup> g<sup>−1</sup>) and tunable densities (2–20 kg m<sup>−3</sup>). The aerogels provide an ideal nanofibrillar substrate for in-situ growth of metal–organic frameworks (MOFs), via co-assembly of MOF precursors with proteins in aqueous solutions. The resulting hybrid aerogels show a nine-fold increase in surface area (810 m<sup>2</sup>g<sup>−1</sup>), with preserved wet stability and additional protein biofunctionality. The hybrid aerogels facilitate a pH-controlled release of immobilized proteins, following a concomitant disassembly of the surface grown MOFs, demonstrating their use in controlled delivery systems. The colorimetric protein binding assay of the biofunctionalized hybrid aerogel also demonstrates the potential of the material as a novel 3D bioassay platform, which could potentially be an alternative to plate-based enzyme-linked immunosorbent assay.</p>}},
author = {{Rostami, Jowan and Gordeyeva, Korneliya and Benselfelt, Tobias and Lahchaichi, Ekeram and Hall, Stephen A. and Riazanova, Anastasia V. and Larsson, Per A. and Cinar Ciftci, Goksu and Wågberg, Lars}},
issn = {{1369-7021}},
keywords = {{3D lightweight materials; Aerogels; Cellulose nanofibrils; Controlled release; Metal–organic frameworks; Protein binding assay}},
language = {{eng}},
pages = {{47--58}},
publisher = {{Elsevier}},
series = {{Materials Today}},
title = {{Hierarchical build-up of bio-based nanofibrous materials with tunable metal–organic framework biofunctionality}},
url = {{http://dx.doi.org/10.1016/j.mattod.2021.04.013}},
doi = {{10.1016/j.mattod.2021.04.013}},
volume = {{48}},
year = {{2021}},
}