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Cost-effectiveness of maintenance treatment with a barrier-strengthening moisturizing cream in patients with atopic dermatitis in Finland, Norway and Sweden

Norrlid, Hanna ; Hjalte, Frida ; Lundqvist, Adam ; Svensson, Åke LU and Ragnarson Tennvall, Gunnel LU (2016) In Acta Dermato-Venereologica 96(2). p.173-176
Abstract
Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active... (More)
Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active ingredients in all 3 countries. The result was confirmed in all but 1 sensitivity analysis. In conclusion, the barrier-strengthening moisturizer is cost-effective as maintenance therapy for patients with atopic dermatitis compared with a moisturizer with no active ingredients. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
96
issue
2
pages
173 - 176
publisher
Medical Journals Limited
external identifiers
  • pmid:26304099
  • scopus:84954472309
  • wos:000373943700005
  • pmid:26304099
ISSN
1651-2057
DOI
10.2340/00015555-2221
language
English
LU publication?
yes
id
d3c75c79-974b-4cca-aa6a-330e77cc4402 (old id 7834941)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26304099?dopt=Abstract
date added to LUP
2016-04-01 13:11:41
date last changed
2022-03-13 22:45:28
@article{d3c75c79-974b-4cca-aa6a-330e77cc4402,
  abstract     = {{Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active ingredients in all 3 countries. The result was confirmed in all but 1 sensitivity analysis. In conclusion, the barrier-strengthening moisturizer is cost-effective as maintenance therapy for patients with atopic dermatitis compared with a moisturizer with no active ingredients.}},
  author       = {{Norrlid, Hanna and Hjalte, Frida and Lundqvist, Adam and Svensson, Åke and Ragnarson Tennvall, Gunnel}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{173--176}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Cost-effectiveness of maintenance treatment with a barrier-strengthening moisturizing cream in patients with atopic dermatitis in Finland, Norway and Sweden}},
  url          = {{https://lup.lub.lu.se/search/files/3215078/8618415}},
  doi          = {{10.2340/00015555-2221}},
  volume       = {{96}},
  year         = {{2016}},
}