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Alcohol abuse partly mediates the association between coronary heart disease and affective or psychotic disorders : a follow-up study in Sweden

Sundquist, K LU and Li, X LU (2006) In Acta Psychiatrica Scandinavica 113(4). p.9-283
Abstract

OBJECTIVE: To analyse whether hospitalization for affective or psychotic disorders predicts coronary heart disease (CHD) after accounting for occupation, region and alcohol-related disorders.

METHOD: National registers were used to identify all individuals in Sweden aged 25-64 years at first hospitalization for affective or psychotic disorders and aged 25-79 years at first hospitalization for CHD between 1987 and 2001. Standardized incidence ratios (SIRs) were calculated.

RESULTS: The association between CHD and affective or psychotic disorders was strongest in the youngest age groups. The overall SIRs varied between 1.39 and 1.68. They were strongly attenuated but remained significant after adjustment for hospitalization... (More)

OBJECTIVE: To analyse whether hospitalization for affective or psychotic disorders predicts coronary heart disease (CHD) after accounting for occupation, region and alcohol-related disorders.

METHOD: National registers were used to identify all individuals in Sweden aged 25-64 years at first hospitalization for affective or psychotic disorders and aged 25-79 years at first hospitalization for CHD between 1987 and 2001. Standardized incidence ratios (SIRs) were calculated.

RESULTS: The association between CHD and affective or psychotic disorders was strongest in the youngest age groups. The overall SIRs varied between 1.39 and 1.68. They were strongly attenuated but remained significant after adjustment for hospitalization because of alcohol-related disorders, especially among women.

CONCLUSION: Hospitalization because of affective or psychotic disorders predicts CHD. These associations are partly mediated by alcohol abuse. Clinicians and decision makers should be aware of the increased risk of CHD in these patient groups.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Aged, Alcoholism/diagnosis, Coronary Disease/epidemiology, Female, Follow-Up Studies, Hospitalization/statistics & numerical data, Humans, International Classification of Diseases, Male, Middle Aged, Mood Disorders/diagnosis, Patient Admission/statistics & numerical data, Prevalence, Psychotic Disorders/diagnosis, Socioeconomic Factors, Sweden/epidemiology
in
Acta Psychiatrica Scandinavica
volume
113
issue
4
pages
7 pages
publisher
Wiley-Blackwell
external identifiers
  • pmid:16638072
  • scopus:33645973554
ISSN
0001-690X
DOI
10.1111/j.1600-0447.2006.00774.x
language
English
LU publication?
no
id
d3e79d87-e207-4e86-98c6-68c85db77720
date added to LUP
2019-01-30 11:13:35
date last changed
2019-11-20 05:36:28
@article{d3e79d87-e207-4e86-98c6-68c85db77720,
  abstract     = {<p>OBJECTIVE: To analyse whether hospitalization for affective or psychotic disorders predicts coronary heart disease (CHD) after accounting for occupation, region and alcohol-related disorders.</p><p>METHOD: National registers were used to identify all individuals in Sweden aged 25-64 years at first hospitalization for affective or psychotic disorders and aged 25-79 years at first hospitalization for CHD between 1987 and 2001. Standardized incidence ratios (SIRs) were calculated.</p><p>RESULTS: The association between CHD and affective or psychotic disorders was strongest in the youngest age groups. The overall SIRs varied between 1.39 and 1.68. They were strongly attenuated but remained significant after adjustment for hospitalization because of alcohol-related disorders, especially among women.</p><p>CONCLUSION: Hospitalization because of affective or psychotic disorders predicts CHD. These associations are partly mediated by alcohol abuse. Clinicians and decision makers should be aware of the increased risk of CHD in these patient groups.</p>},
  author       = {Sundquist, K and Li, X},
  issn         = {0001-690X},
  language     = {eng},
  number       = {4},
  pages        = {9--283},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Psychiatrica Scandinavica},
  title        = {Alcohol abuse partly mediates the association between coronary heart disease and affective or psychotic disorders : a follow-up study in Sweden},
  url          = {http://dx.doi.org/10.1111/j.1600-0447.2006.00774.x},
  doi          = {10.1111/j.1600-0447.2006.00774.x},
  volume       = {113},
  year         = {2006},
}