Colour change in the human histamine wheal made visible by LYYN: a technique to enhance colour differences.
(2010) In Skin Research and Technology 16. p.385-389- Abstract
- Background: Colour differences in photographs can be enhanced using a digital image-processing technique called LYYN. Objective: To investigate colour changes in the histamine wheal after skin prick tests (SPTs). Methods: Histamine SPTs were performed on the forearm of six medical students, and the reactions of the skin were photographed every 2 min for 30 min. Colour differences in the photographs were then enhanced using the LYYN technique. These images were processed using ImageJ to yield numerical values. Results: In the LYYN-processed images, there was a rapid colour change in the histamine wheals between the 18th and the 20th minute (P<0.01). Histamine perfusion in isolated rabbit ears indicated vasodilatation in post-capillary... (More)
- Background: Colour differences in photographs can be enhanced using a digital image-processing technique called LYYN. Objective: To investigate colour changes in the histamine wheal after skin prick tests (SPTs). Methods: Histamine SPTs were performed on the forearm of six medical students, and the reactions of the skin were photographed every 2 min for 30 min. Colour differences in the photographs were then enhanced using the LYYN technique. These images were processed using ImageJ to yield numerical values. Results: In the LYYN-processed images, there was a rapid colour change in the histamine wheals between the 18th and the 20th minute (P<0.01). Histamine perfusion in isolated rabbit ears indicated vasodilatation in post-capillary vessels and desensitized histamine 1 (H1) receptors after a mean of 17 min. It is possible that a similar desensitization takes place in the human histamine wheal, and a study of two histamine SPTs 90 min apart at the same site supports this hypothesis. Conclusion: The LYYN technique was sensitive enough to discover a rapid colour change in the histamine wheal, a change that has not been described before. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1711390
- author
- Holm, Olle ; Lindell, Erik and Malm, Lars LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Skin Research and Technology
- volume
- 16
- pages
- 385 - 389
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000282980800001
- pmid:20923457
- scopus:78650451887
- pmid:20923457
- ISSN
- 0909-752X
- DOI
- 10.1111/j.1600-0846.2010.00457.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Reconstructive Surgery (013240300)
- id
- d41272a5-be77-4181-b68d-3fc1bbb0ff1b (old id 1711390)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20923457?dopt=Abstract
- date added to LUP
- 2016-04-04 08:54:33
- date last changed
- 2022-03-07 22:22:57
@article{d41272a5-be77-4181-b68d-3fc1bbb0ff1b, abstract = {{Background: Colour differences in photographs can be enhanced using a digital image-processing technique called LYYN. Objective: To investigate colour changes in the histamine wheal after skin prick tests (SPTs). Methods: Histamine SPTs were performed on the forearm of six medical students, and the reactions of the skin were photographed every 2 min for 30 min. Colour differences in the photographs were then enhanced using the LYYN technique. These images were processed using ImageJ to yield numerical values. Results: In the LYYN-processed images, there was a rapid colour change in the histamine wheals between the 18th and the 20th minute (P<0.01). Histamine perfusion in isolated rabbit ears indicated vasodilatation in post-capillary vessels and desensitized histamine 1 (H1) receptors after a mean of 17 min. It is possible that a similar desensitization takes place in the human histamine wheal, and a study of two histamine SPTs 90 min apart at the same site supports this hypothesis. Conclusion: The LYYN technique was sensitive enough to discover a rapid colour change in the histamine wheal, a change that has not been described before.}}, author = {{Holm, Olle and Lindell, Erik and Malm, Lars}}, issn = {{0909-752X}}, language = {{eng}}, pages = {{385--389}}, publisher = {{Wiley-Blackwell}}, series = {{Skin Research and Technology}}, title = {{Colour change in the human histamine wheal made visible by LYYN: a technique to enhance colour differences.}}, url = {{http://dx.doi.org/10.1111/j.1600-0846.2010.00457.x}}, doi = {{10.1111/j.1600-0846.2010.00457.x}}, volume = {{16}}, year = {{2010}}, }