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Seroprevalencia de anticuerpos a virus del sarampión, rubeola, parotiditis, hepatitis B y los tres serotipos de poliovirus, en niños de Quindío, Colombia

González, María M.; Sarmiento-Pérez, Luis LU ; Giraldo, Alejandra M.; Padilla, Leonardo; Rey-Benito, Gloria and Castaño, Jhon C. (2016) In Revista de Salud Publica 18(1). p.95-103
Abstract

Objective: The main goal of this research was to assess the seroprevalence of antibodies against measles, rubella, mumps, hepatitis B and all three poliovirus serotypes among children in the Quindio Department, Colombia. Methods: Blood samples were obtained from 170 healthy children aged 5-9 years from nine municipalities in Quindio. The presence of serum IgG antibodies against measles, rubella, mumps and Hepatitis B were determined using commercial indirect ELISA kits. Immunity to poliomyelitis was assessed through the presence of neutralizing antibodies following the method recommended by the World Health Organization. Results: Among the 170 children enrolled, 169 (99.41%), 170(100 %), and 167 (98.2 %) were seropositive to poliovirus... (More)

Objective: The main goal of this research was to assess the seroprevalence of antibodies against measles, rubella, mumps, hepatitis B and all three poliovirus serotypes among children in the Quindio Department, Colombia. Methods: Blood samples were obtained from 170 healthy children aged 5-9 years from nine municipalities in Quindio. The presence of serum IgG antibodies against measles, rubella, mumps and Hepatitis B were determined using commercial indirect ELISA kits. Immunity to poliomyelitis was assessed through the presence of neutralizing antibodies following the method recommended by the World Health Organization. Results: Among the 170 children enrolled, 169 (99.41%), 170(100 %), and 167 (98.2 %) were seropositive to poliovirus 1, poliovirus 2, and poliovirus 3, respectively. The average reciprocal antibody titers were 178 for poliovirus type 1, 120 for type 2 and 56 for type 3. Of the 170 children, 96.47 % were protected against mumps and rubella, and 86.47 % against measles. Only 106 (62.35 %) of the studied subjects were proved to be seropositive to hepatitis B. Conclusion: The immunization program in Quindio has provided seroprotection against all three poliomyelitis serotypes, rubella and mumps. However, the child population is not fully protected against measles and hepatitis B virus infections.

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author
organization
alternative title
Seroprevalence of antibodies to measles, rubella, mumps, hepatitis B viruses and all three poliovirus serotypes among children in Quindío, Colombia
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Hepatitis B, Measles, Poliomyelitis, Seroepidemiologic studies, Vaccines
in
Revista de Salud Publica
volume
18
issue
1
pages
9 pages
publisher
Universidad Nacional de Colombia
external identifiers
  • scopus:84964886819
ISSN
0124-0064
DOI
10.15446/rsap.v18n1.44514
language
Spanish
LU publication?
yes
id
d4c88776-3c3c-4dbf-92bb-a84d518dadaf
date added to LUP
2016-06-01 12:55:23
date last changed
2017-01-01 08:27:20
@article{d4c88776-3c3c-4dbf-92bb-a84d518dadaf,
  abstract     = {<p>Objective: The main goal of this research was to assess the seroprevalence of antibodies against measles, rubella, mumps, hepatitis B and all three poliovirus serotypes among children in the Quindio Department, Colombia. Methods: Blood samples were obtained from 170 healthy children aged 5-9 years from nine municipalities in Quindio. The presence of serum IgG antibodies against measles, rubella, mumps and Hepatitis B were determined using commercial indirect ELISA kits. Immunity to poliomyelitis was assessed through the presence of neutralizing antibodies following the method recommended by the World Health Organization. Results: Among the 170 children enrolled, 169 (99.41%), 170(100 %), and 167 (98.2 %) were seropositive to poliovirus 1, poliovirus 2, and poliovirus 3, respectively. The average reciprocal antibody titers were 178 for poliovirus type 1, 120 for type 2 and 56 for type 3. Of the 170 children, 96.47 % were protected against mumps and rubella, and 86.47 % against measles. Only 106 (62.35 %) of the studied subjects were proved to be seropositive to hepatitis B. Conclusion: The immunization program in Quindio has provided seroprotection against all three poliomyelitis serotypes, rubella and mumps. However, the child population is not fully protected against measles and hepatitis B virus infections.</p>},
  author       = {González, María M. and Sarmiento-Pérez, Luis and Giraldo, Alejandra M. and Padilla, Leonardo and Rey-Benito, Gloria and Castaño, Jhon C.},
  issn         = {0124-0064},
  keyword      = {Hepatitis B,Measles,Poliomyelitis,Seroepidemiologic studies,Vaccines},
  language     = {spa},
  month        = {01},
  number       = {1},
  pages        = {95--103},
  publisher    = {Universidad Nacional de Colombia},
  series       = {Revista de Salud Publica},
  title        = {Seroprevalencia de anticuerpos a virus del sarampión, rubeola, parotiditis, hepatitis B y los tres serotipos de poliovirus, en niños de Quindío, Colombia},
  url          = {http://dx.doi.org/10.15446/rsap.v18n1.44514},
  volume       = {18},
  year         = {2016},
}