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COVID-19 vaccination in autoimmune disease (COVAD) survey protocol

Sen, Parikshit ; Gupta, Latika ; Lilleker, James B. ; Aggarwal, Vishwesh ; Kardes, Sinan ; Milchert, Marcin ; Gheita, Tamer ; Salim, Babur ; Velikova, Tsvetelina and Gracia-Ramos, Abraham Edgar , et al. (2022) In Rheumatology International 42(1). p.23-29
Abstract

The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution to reducing poor clinical outcomes, vaccine hesitancy continues to be an obstacle to achieving high levels of vaccine uptake. This represents particular risk to patients with autoimmune diseases, a group already at increased risk of hospitalization and poor clinical outcomes related to COVID-19 infection. Whilst there is a paucity of long-term safety and efficacy data of COVID-19 vaccination in patients with autoimmune diseases, the current evidence strongly suggests that the benefits of vaccination outweigh the risks of adverse effects and disease... (More)

The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution to reducing poor clinical outcomes, vaccine hesitancy continues to be an obstacle to achieving high levels of vaccine uptake. This represents particular risk to patients with autoimmune diseases, a group already at increased risk of hospitalization and poor clinical outcomes related to COVID-19 infection. Whilst there is a paucity of long-term safety and efficacy data of COVID-19 vaccination in patients with autoimmune diseases, the current evidence strongly suggests that the benefits of vaccination outweigh the risks of adverse effects and disease flares. Herein, we report the protocol of the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study, an ongoing international collaborative study involving 29 countries and over 110 investigators.

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@article{d52e927e-b8d6-4b6e-acab-744b9cae50ad,
  abstract     = {{<p>The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution to reducing poor clinical outcomes, vaccine hesitancy continues to be an obstacle to achieving high levels of vaccine uptake. This represents particular risk to patients with autoimmune diseases, a group already at increased risk of hospitalization and poor clinical outcomes related to COVID-19 infection. Whilst there is a paucity of long-term safety and efficacy data of COVID-19 vaccination in patients with autoimmune diseases, the current evidence strongly suggests that the benefits of vaccination outweigh the risks of adverse effects and disease flares. Herein, we report the protocol of the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study, an ongoing international collaborative study involving 29 countries and over 110 investigators.</p>}},
  author       = {{Sen, Parikshit and Gupta, Latika and Lilleker, James B. and Aggarwal, Vishwesh and Kardes, Sinan and Milchert, Marcin and Gheita, Tamer and Salim, Babur and Velikova, Tsvetelina and Gracia-Ramos, Abraham Edgar and Parodis, Ioannis and O'Callaghan, Albert Selva and Nikiphorou, Elena and Tan, Ai Lyn and Cavagna, Lorenzo and Saavedra, Miguel A. and Shinjo, Samuel Katsuyuki and Ziade, Nelly and Knitza, Johannes and Kuwana, Masataka and Cagnotto, Giovanni and Nune, Arvind and Distler, Oliver and Chinoy, Hector and Aggarwal, Vikas and Aggarwal, Rohit}},
  issn         = {{1437-160X}},
  keywords     = {{Autoimmune diseases; COVAD; COVID-19; Survey; Vaccination}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{23--29}},
  publisher    = {{Springer}},
  series       = {{Rheumatology International}},
  title        = {{COVID-19 vaccination in autoimmune disease (COVAD) survey protocol}},
  url          = {{http://dx.doi.org/10.1007/s00296-021-05046-4}},
  doi          = {{10.1007/s00296-021-05046-4}},
  volume       = {{42}},
  year         = {{2022}},
}