Electrochemistry of guanine and 8-oxoguanine at gold electrodes
(2004) In Electrochimica Acta 49(11). p.1751-1759- Abstract
- Guanine was electrochemically oxidised at polycrystalline gold electrodes. The potential for guanine oxidation at pH 7.4 was +690 mV versus AgAgCl when extrapolated to a scan rate of 3 mV s(-1). Kinetic analysis revealed the initial irreversible 2e(-) oxidation of guanine, achieved with fast scan cyclic voltammetry. At scan rates lower than 5 V s(-1), the 2e(-) oxidation changed to the extensive 4e(-) one. The initial 2e- oxidation of guanine, observed in the first scan, resulted in a quasi-reversible 1e(-) redox process of the oxidation product in the following scans, with a formal potential (E-o/) of +263 mV. This correlated well with the redox transformations of 8-oxo-7,8-dihydroguanine (8-oxoguanine, 8-oxoG). The kinetics of guanine... (More)
- Guanine was electrochemically oxidised at polycrystalline gold electrodes. The potential for guanine oxidation at pH 7.4 was +690 mV versus AgAgCl when extrapolated to a scan rate of 3 mV s(-1). Kinetic analysis revealed the initial irreversible 2e(-) oxidation of guanine, achieved with fast scan cyclic voltammetry. At scan rates lower than 5 V s(-1), the 2e(-) oxidation changed to the extensive 4e(-) one. The initial 2e- oxidation of guanine, observed in the first scan, resulted in a quasi-reversible 1e(-) redox process of the oxidation product in the following scans, with a formal potential (E-o/) of +263 mV. This correlated well with the redox transformations of 8-oxo-7,8-dihydroguanine (8-oxoguanine, 8-oxoG). The kinetics of guanine oxidation on gold is discussed in detail within Laviron's approach and compared with that of 8-oxoG. (C) 2003 Elsevier Ltd. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/286171
- author
- Ferapontova, Elena LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- polycrystalline gold, electrochemical oxidation, guanine, 8-oxoguanine
- in
- Electrochimica Acta
- volume
- 49
- issue
- 11
- pages
- 1751 - 1759
- publisher
- Pergamon Press Ltd.
- external identifiers
-
- wos:000220018600006
- scopus:1142304491
- ISSN
- 0013-4686
- DOI
- 10.1016/j.electacta.2003.12.006
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
- id
- d5e3f792-51e3-4622-9278-03d3d9aa8dec (old id 286171)
- date added to LUP
- 2016-04-01 11:36:14
- date last changed
- 2022-04-20 19:02:58
@article{d5e3f792-51e3-4622-9278-03d3d9aa8dec,
abstract = {{Guanine was electrochemically oxidised at polycrystalline gold electrodes. The potential for guanine oxidation at pH 7.4 was +690 mV versus AgAgCl when extrapolated to a scan rate of 3 mV s(-1). Kinetic analysis revealed the initial irreversible 2e(-) oxidation of guanine, achieved with fast scan cyclic voltammetry. At scan rates lower than 5 V s(-1), the 2e(-) oxidation changed to the extensive 4e(-) one. The initial 2e- oxidation of guanine, observed in the first scan, resulted in a quasi-reversible 1e(-) redox process of the oxidation product in the following scans, with a formal potential (E-o/) of +263 mV. This correlated well with the redox transformations of 8-oxo-7,8-dihydroguanine (8-oxoguanine, 8-oxoG). The kinetics of guanine oxidation on gold is discussed in detail within Laviron's approach and compared with that of 8-oxoG. (C) 2003 Elsevier Ltd. All rights reserved.}},
author = {{Ferapontova, Elena}},
issn = {{0013-4686}},
keywords = {{polycrystalline gold; electrochemical oxidation; guanine; 8-oxoguanine}},
language = {{eng}},
number = {{11}},
pages = {{1751--1759}},
publisher = {{Pergamon Press Ltd.}},
series = {{Electrochimica Acta}},
title = {{Electrochemistry of guanine and 8-oxoguanine at gold electrodes}},
url = {{http://dx.doi.org/10.1016/j.electacta.2003.12.006}},
doi = {{10.1016/j.electacta.2003.12.006}},
volume = {{49}},
year = {{2004}},
}