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A Rigid Disc for Protection of Exposed Blood Vessels During Negative Pressure Wound Therapy

Anesater, Erik; Borgquist, Ola LU ; Torbrand, Christian LU ; Roupé, Markus LU ; Ingemansson, Richard LU ; Lindstedt Ingemansson, Sandra LU and Malmsjö, Malin LU (2013) In Surgical Innovation 20(1). p.74-80
Abstract
Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery... (More)
Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored. Conclusions. NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
experimental surgery, wound healing, negative pressure wound therapy, microvascular blood flow
in
Surgical Innovation
volume
20
issue
1
pages
74 - 80
publisher
SAGE Publications Inc.
external identifiers
  • wos:000327370800019
  • scopus:84872329220
ISSN
1553-3506
DOI
10.1177/1553350612444169
language
English
LU publication?
yes
id
d5f21d34-4f31-4f2d-be57-bbf88ae3325c (old id 3470729)
date added to LUP
2013-03-01 07:46:45
date last changed
2019-02-20 01:31:08
@article{d5f21d34-4f31-4f2d-be57-bbf88ae3325c,
  abstract     = {Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored. Conclusions. NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow.},
  author       = {Anesater, Erik and Borgquist, Ola and Torbrand, Christian and Roupé, Markus and Ingemansson, Richard and Lindstedt Ingemansson, Sandra and Malmsjö, Malin},
  issn         = {1553-3506},
  keyword      = {experimental surgery,wound healing,negative pressure wound therapy,microvascular blood flow},
  language     = {eng},
  number       = {1},
  pages        = {74--80},
  publisher    = {SAGE Publications Inc.},
  series       = {Surgical Innovation},
  title        = {A Rigid Disc for Protection of Exposed Blood Vessels During Negative Pressure Wound Therapy},
  url          = {http://dx.doi.org/10.1177/1553350612444169},
  volume       = {20},
  year         = {2013},
}