A Rigid Disc for Protection of Exposed Blood Vessels During Negative Pressure Wound Therapy
(2013) In Surgical Innovation 20(1). p.74-80- Abstract
- Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery... (More)
- Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored. Conclusions. NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3470729
- author
- Anesater, Erik ; Borgquist, Ola LU ; Torbrand, Christian LU ; Roupé, Markus LU ; Ingemansson, Richard LU ; Lindstedt Ingemansson, Sandra LU and Malmsjö, Malin LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- experimental surgery, wound healing, negative pressure wound therapy, microvascular blood flow
- in
- Surgical Innovation
- volume
- 20
- issue
- 1
- pages
- 74 - 80
- publisher
- SAGE Publications
- external identifiers
-
- wos:000327370800019
- scopus:84872329220
- pmid:22517331
- ISSN
- 1553-3506
- DOI
- 10.1177/1553350612444169
- language
- English
- LU publication?
- yes
- id
- d5f21d34-4f31-4f2d-be57-bbf88ae3325c (old id 3470729)
- date added to LUP
- 2016-04-01 10:05:34
- date last changed
- 2022-01-25 19:34:32
@article{d5f21d34-4f31-4f2d-be57-bbf88ae3325c, abstract = {{Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored. Conclusions. NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow.}}, author = {{Anesater, Erik and Borgquist, Ola and Torbrand, Christian and Roupé, Markus and Ingemansson, Richard and Lindstedt Ingemansson, Sandra and Malmsjö, Malin}}, issn = {{1553-3506}}, keywords = {{experimental surgery; wound healing; negative pressure wound therapy; microvascular blood flow}}, language = {{eng}}, number = {{1}}, pages = {{74--80}}, publisher = {{SAGE Publications}}, series = {{Surgical Innovation}}, title = {{A Rigid Disc for Protection of Exposed Blood Vessels During Negative Pressure Wound Therapy}}, url = {{http://dx.doi.org/10.1177/1553350612444169}}, doi = {{10.1177/1553350612444169}}, volume = {{20}}, year = {{2013}}, }