Potentiometric propranolol-selective sensor based on molecularly imprinted polymer
Gurtova, O. ; Ye, Lei LU
and Chmilenko, F.
(2013)
In Analytical and Bioanalytical Chemistry
405(1).
p.287-295
- Abstract
- A novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show near-Nernstian responses down to 10(-4)-10(-5) M propranolol concentration. The potentiometric response of MIP-based sensor for propranolol in mixed nonaqueous medium was shown at first. Sensor selectivity relative to various inorganic cations, atenolol and metoprolol, was reported. Direct potentiometry was used to determine propranolol in aqueous modeling solutions and pharmaceutical preparations with good results.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3480990
- author
- Gurtova, O.
; Ye, Lei
LU
and Chmilenko, F.
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Molecular imprinted polymer, Propranolol, Potentiometric sensor, Nanoparticles, Anaprilin
- in
- Analytical and Bioanalytical Chemistry
- volume
- 405
- issue
- 1
- pages
- 287 - 295
- publisher
- Springer
- external identifiers
-
- wos:000313064000028
- scopus:84872290164
- pmid:23104313
- ISSN
- 1618-2642
- DOI
- 10.1007/s00216-012-6493-6
- language
- English
- LU publication?
- yes
- id
- d6b2b379-1d5a-4e61-86c0-b4ba9bfd3152 (old id 3480990)
- date added to LUP
- 2016-04-01 11:02:16
- date last changed
- 2022-01-26 04:53:54
@article{d6b2b379-1d5a-4e61-86c0-b4ba9bfd3152,
abstract = {{A novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show near-Nernstian responses down to 10(-4)-10(-5) M propranolol concentration. The potentiometric response of MIP-based sensor for propranolol in mixed nonaqueous medium was shown at first. Sensor selectivity relative to various inorganic cations, atenolol and metoprolol, was reported. Direct potentiometry was used to determine propranolol in aqueous modeling solutions and pharmaceutical preparations with good results.}},
author = {{Gurtova, O. and Ye, Lei and Chmilenko, F.}},
issn = {{1618-2642}},
keywords = {{Molecular imprinted polymer; Propranolol; Potentiometric sensor; Nanoparticles; Anaprilin}},
language = {{eng}},
number = {{1}},
pages = {{287--295}},
publisher = {{Springer}},
series = {{Analytical and Bioanalytical Chemistry}},
title = {{Potentiometric propranolol-selective sensor based on molecularly imprinted polymer}},
url = {{http://dx.doi.org/10.1007/s00216-012-6493-6}},
doi = {{10.1007/s00216-012-6493-6}},
volume = {{405}},
year = {{2013}},
}