A facile method for preparing molecularly imprinted polymer spheres using spherical silica templates
(2002) In Journal of Materials Chemistry 12(5). p.1577-1581- Abstract
- A novel and facile preparation method for spherical molecularly imprinted polymer (MIP) beads is presented. Two types of beads were synthesized and investigated: (i) silica-MIP composites were obtained by filling spherical, porous C-4-coated silica beads with print molecule and monomers followed by polymerisation; (ii) spherical molecularly imprinted polymer beads were acquired mirroring the silica particles in size, shape and pore structure by removing the silica matrix from the silica-MIP composites. With regard to their chromatographic properties and yield of the materials both types of particle were more advantageous compared to irregularly shaped traditional MIPs. Also the work-up time to obtain imprinted spherical particles is... (More)
- A novel and facile preparation method for spherical molecularly imprinted polymer (MIP) beads is presented. Two types of beads were synthesized and investigated: (i) silica-MIP composites were obtained by filling spherical, porous C-4-coated silica beads with print molecule and monomers followed by polymerisation; (ii) spherical molecularly imprinted polymer beads were acquired mirroring the silica particles in size, shape and pore structure by removing the silica matrix from the silica-MIP composites. With regard to their chromatographic properties and yield of the materials both types of particle were more advantageous compared to irregularly shaped traditional MIPs. Also the work-up time to obtain imprinted spherical particles is greatly reduced compared to traditional methods using polymer monoliths, which have to be ground, sieved and sedimented. Generally, the described method may open new possibilities for synthesis of novel types of imprinted polymer formats such as membranes, bulk polymers, films or in-situ columns using appropriate support or sacrificial materials. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/339921
- author
- Yilmaz, Ecevit LU ; Ramstrom, O ; Moller, P ; Sanchez, D and Mosbach, Klaus LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Materials Chemistry
- volume
- 12
- issue
- 5
- pages
- 1577 - 1581
- publisher
- Royal Society of Chemistry
- external identifiers
-
- wos:000175143000062
- scopus:0036097274
- ISSN
- 1364-5501
- DOI
- 10.1039/b109262f
- language
- English
- LU publication?
- yes
- id
- d6e392ab-72d9-4488-9465-b69d9fd975f6 (old id 339921)
- date added to LUP
- 2016-04-01 11:35:06
- date last changed
- 2022-03-28 00:14:45
@article{d6e392ab-72d9-4488-9465-b69d9fd975f6,
abstract = {{A novel and facile preparation method for spherical molecularly imprinted polymer (MIP) beads is presented. Two types of beads were synthesized and investigated: (i) silica-MIP composites were obtained by filling spherical, porous C-4-coated silica beads with print molecule and monomers followed by polymerisation; (ii) spherical molecularly imprinted polymer beads were acquired mirroring the silica particles in size, shape and pore structure by removing the silica matrix from the silica-MIP composites. With regard to their chromatographic properties and yield of the materials both types of particle were more advantageous compared to irregularly shaped traditional MIPs. Also the work-up time to obtain imprinted spherical particles is greatly reduced compared to traditional methods using polymer monoliths, which have to be ground, sieved and sedimented. Generally, the described method may open new possibilities for synthesis of novel types of imprinted polymer formats such as membranes, bulk polymers, films or in-situ columns using appropriate support or sacrificial materials.}},
author = {{Yilmaz, Ecevit and Ramstrom, O and Moller, P and Sanchez, D and Mosbach, Klaus}},
issn = {{1364-5501}},
language = {{eng}},
number = {{5}},
pages = {{1577--1581}},
publisher = {{Royal Society of Chemistry}},
series = {{Journal of Materials Chemistry}},
title = {{A facile method for preparing molecularly imprinted polymer spheres using spherical silica templates}},
url = {{http://dx.doi.org/10.1039/b109262f}},
doi = {{10.1039/b109262f}},
volume = {{12}},
year = {{2002}},
}