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Fine-Needle Aspiration of Parotid Gland Sialoblastoma. Two New Cases and Literature Review

Bakula-Zalewska, Elwira ; Domanski, Henryk A. LU and Klijanienko, Jerzy (2025) In Diagnostic Cytopathology 53(8). p.155-159
Abstract

Sialoblastoma is an exceedingly rare, low-grade malignancy, most frequently arising in the parotid gland. Only four case reports detailing the cytomorphology of this neoplasm exist in the English literature. Here, we describe the cytological features, histopathology, and clinical data of sialoblastomas presented at birth in two additional patients. Both neoplasms were initially examined by fine-needle aspiration (FNA) followed by surgical excision of the tumors. Smears showed hypercellularity and basaloid round to oval cells isolated or arranged in three-dimensional clusters. Papillary and acinar configurations, metachromatic pink stromal fragments, and hyaline globules were also present. One case was diagnosed as a neoplasm of unclear... (More)

Sialoblastoma is an exceedingly rare, low-grade malignancy, most frequently arising in the parotid gland. Only four case reports detailing the cytomorphology of this neoplasm exist in the English literature. Here, we describe the cytological features, histopathology, and clinical data of sialoblastomas presented at birth in two additional patients. Both neoplasms were initially examined by fine-needle aspiration (FNA) followed by surgical excision of the tumors. Smears showed hypercellularity and basaloid round to oval cells isolated or arranged in three-dimensional clusters. Papillary and acinar configurations, metachromatic pink stromal fragments, and hyaline globules were also present. One case was diagnosed as a neoplasm of unclear malignant potential and the second as malignant.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cytology, fine-needle aspiration, immunocytochemistry, salivary gland tumor, Sialoblastoma
in
Diagnostic Cytopathology
volume
53
issue
8
pages
155 - 159
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:40331495
  • scopus:105004358240
ISSN
8755-1039
DOI
10.1002/dc.25480
language
English
LU publication?
yes
id
d7f1ca13-164d-4667-8090-2b406d39b0ac
date added to LUP
2025-09-16 10:19:55
date last changed
2025-09-30 12:01:23
@article{d7f1ca13-164d-4667-8090-2b406d39b0ac,
  abstract     = {{<p>Sialoblastoma is an exceedingly rare, low-grade malignancy, most frequently arising in the parotid gland. Only four case reports detailing the cytomorphology of this neoplasm exist in the English literature. Here, we describe the cytological features, histopathology, and clinical data of sialoblastomas presented at birth in two additional patients. Both neoplasms were initially examined by fine-needle aspiration (FNA) followed by surgical excision of the tumors. Smears showed hypercellularity and basaloid round to oval cells isolated or arranged in three-dimensional clusters. Papillary and acinar configurations, metachromatic pink stromal fragments, and hyaline globules were also present. One case was diagnosed as a neoplasm of unclear malignant potential and the second as malignant.</p>}},
  author       = {{Bakula-Zalewska, Elwira and Domanski, Henryk A. and Klijanienko, Jerzy}},
  issn         = {{8755-1039}},
  keywords     = {{cytology; fine-needle aspiration; immunocytochemistry; salivary gland tumor; Sialoblastoma}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{155--159}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Diagnostic Cytopathology}},
  title        = {{Fine-Needle Aspiration of Parotid Gland Sialoblastoma. Two New Cases and Literature Review}},
  url          = {{http://dx.doi.org/10.1002/dc.25480}},
  doi          = {{10.1002/dc.25480}},
  volume       = {{53}},
  year         = {{2025}},
}