Kick-starting the cancer-immunity cycle by targeting CD40
(2015) In OncoImmunology 4(7). p.1011484-1011484- Abstract
- Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for combination regimens.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7596483
- author
- Ellmark, Peter LU ; Mangsbo, S. M. ; Furebring, C. ; Totterman, T. H. and Norlen, P.
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- CD40, PD-1, agonistic antibody, immunooncology
- in
- OncoImmunology
- volume
- 4
- issue
- 7
- pages
- 1011484 - 1011484
- publisher
- Landes Bioscience
- external identifiers
-
- wos:000356964800002
- pmid:26140231
- scopus:84944453397
- pmid:26140231
- ISSN
- 2162-4011
- DOI
- 10.1080/2162402X.2015.1011484
- language
- English
- LU publication?
- yes
- id
- d878c92b-517a-44d0-9220-7543c0873d02 (old id 7596483)
- date added to LUP
- 2016-04-01 10:22:20
- date last changed
- 2023-02-22 09:17:01
@misc{d878c92b-517a-44d0-9220-7543c0873d02, abstract = {{Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for combination regimens.}}, author = {{Ellmark, Peter and Mangsbo, S. M. and Furebring, C. and Totterman, T. H. and Norlen, P.}}, issn = {{2162-4011}}, keywords = {{CD40; PD-1; agonistic antibody; immunooncology}}, language = {{eng}}, number = {{7}}, pages = {{1011484--1011484}}, publisher = {{Landes Bioscience}}, series = {{OncoImmunology}}, title = {{Kick-starting the cancer-immunity cycle by targeting CD40}}, url = {{http://dx.doi.org/10.1080/2162402X.2015.1011484}}, doi = {{10.1080/2162402X.2015.1011484}}, volume = {{4}}, year = {{2015}}, }