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Recent Advances in the Use of Molecularly Imprinted Materials in Separation and Synthesis

Ramström, Olof ; Ye, Lei LU orcid ; Yu, Cong LU and Gustavsson, Per Erik LU (1998) In ACS Symposium Series 703. p.82-89
Abstract

Molecularly imprinted materials, prepared using self-assembly imprinting protocols using only non-covalent interactions, can be used as chromatography media in aqueous phase. The recognition properties are highly dependent on the interacting species used in the imprinting protocol. Ionic interactions, together with strong hydrogen bonding, represent useful means of obtaining recognition. With increasing levels of water in the recognition media, the hydrophobic effect comes into play. Molecularly imprinted materials can furthermore be used as auxiliary agents in enzymatic syntheses in water-saturated organic phases. When materials molecularly imprinted for the reaction product were applied to the thermolysin-catalyzed aspartame... (More)

Molecularly imprinted materials, prepared using self-assembly imprinting protocols using only non-covalent interactions, can be used as chromatography media in aqueous phase. The recognition properties are highly dependent on the interacting species used in the imprinting protocol. Ionic interactions, together with strong hydrogen bonding, represent useful means of obtaining recognition. With increasing levels of water in the recognition media, the hydrophobic effect comes into play. Molecularly imprinted materials can furthermore be used as auxiliary agents in enzymatic syntheses in water-saturated organic phases. When materials molecularly imprinted for the reaction product were applied to the thermolysin-catalyzed aspartame synthesis, an increase in yield was observed. Introduction of a thermodynamic trap provided by the molecularly imprinted matrices allowed a non-favorable equilibrium for the thermolysin reaction to be pushed in the forward direction.

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Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Molecular and Ionic Recognition with Imprinted Polymers
series title
ACS Symposium Series
editor
Bartsch, Richard A. and Maeda, Mizuo
volume
703
pages
8 pages
external identifiers
  • scopus:0345983483
ISSN
0097-6156
ISBN
9780841235748
9780841216853
DOI
10.1021/bk-1998-0703.ch005
language
English
LU publication?
yes
id
d8ae890d-86d1-48cd-bde9-109578e311b2
date added to LUP
2019-06-18 09:04:05
date last changed
2024-01-01 21:11:46
@inbook{d8ae890d-86d1-48cd-bde9-109578e311b2,
  abstract     = {{<p>Molecularly imprinted materials, prepared using self-assembly imprinting protocols using only non-covalent interactions, can be used as chromatography media in aqueous phase. The recognition properties are highly dependent on the interacting species used in the imprinting protocol. Ionic interactions, together with strong hydrogen bonding, represent useful means of obtaining recognition. With increasing levels of water in the recognition media, the hydrophobic effect comes into play. Molecularly imprinted materials can furthermore be used as auxiliary agents in enzymatic syntheses in water-saturated organic phases. When materials molecularly imprinted for the reaction product were applied to the thermolysin-catalyzed aspartame synthesis, an increase in yield was observed. Introduction of a thermodynamic trap provided by the molecularly imprinted matrices allowed a non-favorable equilibrium for the thermolysin reaction to be pushed in the forward direction.</p>}},
  author       = {{Ramström, Olof and Ye, Lei and Yu, Cong and Gustavsson, Per Erik}},
  booktitle    = {{Molecular and Ionic Recognition with Imprinted Polymers}},
  editor       = {{Bartsch, Richard A. and Maeda, Mizuo}},
  isbn         = {{9780841235748}},
  issn         = {{0097-6156}},
  language     = {{eng}},
  month        = {{05}},
  pages        = {{82--89}},
  series       = {{ACS Symposium Series}},
  title        = {{Recent Advances in the Use of Molecularly Imprinted Materials in Separation and Synthesis}},
  url          = {{http://dx.doi.org/10.1021/bk-1998-0703.ch005}},
  doi          = {{10.1021/bk-1998-0703.ch005}},
  volume       = {{703}},
  year         = {{1998}},
}