A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate
(2021) In Molecular and Cellular Oncology 8(5).- Abstract
The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d9096ae9-7a2d-4011-96fe-b07cc1882c94
- author
- Ho, James C.S. LU ; Ambite, Ines LU ; Mok, K. H. LU ; Babjuk, Marek and Svanborg, Catharina LU
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bladder cancer, low toxicity, Novel cancer therapy, peptide-oleate complex, protein folding
- in
- Molecular and Cellular Oncology
- volume
- 8
- issue
- 5
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:85116386998
- pmid:34859140
- ISSN
- 2372-3556
- DOI
- 10.1080/23723556.2021.1974278
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.
- id
- d9096ae9-7a2d-4011-96fe-b07cc1882c94
- date added to LUP
- 2021-10-25 15:13:09
- date last changed
- 2024-09-22 04:07:24
@article{d9096ae9-7a2d-4011-96fe-b07cc1882c94, abstract = {{<p>The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.</p>}}, author = {{Ho, James C.S. and Ambite, Ines and Mok, K. H. and Babjuk, Marek and Svanborg, Catharina}}, issn = {{2372-3556}}, keywords = {{bladder cancer; low toxicity; Novel cancer therapy; peptide-oleate complex; protein folding}}, language = {{eng}}, number = {{5}}, publisher = {{Taylor & Francis}}, series = {{Molecular and Cellular Oncology}}, title = {{A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate}}, url = {{http://dx.doi.org/10.1080/23723556.2021.1974278}}, doi = {{10.1080/23723556.2021.1974278}}, volume = {{8}}, year = {{2021}}, }