Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate

Ho, James C.S. LU ; Ambite, Ines LU orcid ; Mok, K. H. LU ; Babjuk, Marek and Svanborg, Catharina LU (2021) In Molecular and Cellular Oncology 8(5).
Abstract

The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.

Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bladder cancer, low toxicity, Novel cancer therapy, peptide-oleate complex, protein folding
in
Molecular and Cellular Oncology
volume
8
issue
5
publisher
Taylor & Francis
external identifiers
  • pmid:34859140
  • scopus:85116386998
ISSN
2372-3556
DOI
10.1080/23723556.2021.1974278
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.
id
d9096ae9-7a2d-4011-96fe-b07cc1882c94
date added to LUP
2021-10-25 15:13:09
date last changed
2025-10-14 11:20:26
@article{d9096ae9-7a2d-4011-96fe-b07cc1882c94,
  abstract     = {{<p>The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.</p>}},
  author       = {{Ho, James C.S. and Ambite, Ines and Mok, K. H. and Babjuk, Marek and Svanborg, Catharina}},
  issn         = {{2372-3556}},
  keywords     = {{bladder cancer; low toxicity; Novel cancer therapy; peptide-oleate complex; protein folding}},
  language     = {{eng}},
  number       = {{5}},
  publisher    = {{Taylor & Francis}},
  series       = {{Molecular and Cellular Oncology}},
  title        = {{A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate}},
  url          = {{http://dx.doi.org/10.1080/23723556.2021.1974278}},
  doi          = {{10.1080/23723556.2021.1974278}},
  volume       = {{8}},
  year         = {{2021}},
}