Fusion of the FUS and ATF1 genes in a large, deep-seated angiomatoid fibrous histiocytoma
(2002) In Diagnostic Molecular Pathology 11(3). p.157-162- Abstract
- We report a case of a large, deep-seated, diagnostically difficult angiomatoid fibrous histiocytoma. The neoplastic cells were positive for vimentin, calponin, CD99, and, focally, for desmin and contained intertwining cytoplasmic processes joined by desmosomelike junctions. Fusion of codon 175 of the FUS gene to codon 110 of the ATF1 gene was detected by reverse transcription-polymerase chain reaction. Because identical fusion of the FUS and ATF1 genes has been recently reported in another case of angiomatoid fibrous histiocytoma, fusion of these genes may be characteristic for at least a subset of these tumors.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/330132
- author
- Raddaoui, E ; Donner, L and Panagopoulos, Ioannis LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- molecular biology, ultrastructure, angiomatoid fibrous histiocytoma, immunohistochemistry, FUS gene, ATF1 gene
- in
- Diagnostic Molecular Pathology
- volume
- 11
- issue
- 3
- pages
- 157 - 162
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:12218455
- wos:000177638600006
- scopus:0036707752
- ISSN
- 1052-9551
- language
- English
- LU publication?
- yes
- id
- db6611b4-df07-43fd-958a-51d397ec6c9e (old id 330132)
- alternative location
- http://www.molecularpathology.com/pt/re/dmp/abstract.00019606-200209000-00006.htm
- date added to LUP
- 2016-04-01 16:03:52
- date last changed
- 2022-04-22 19:20:57
@article{db6611b4-df07-43fd-958a-51d397ec6c9e,
abstract = {{We report a case of a large, deep-seated, diagnostically difficult angiomatoid fibrous histiocytoma. The neoplastic cells were positive for vimentin, calponin, CD99, and, focally, for desmin and contained intertwining cytoplasmic processes joined by desmosomelike junctions. Fusion of codon 175 of the FUS gene to codon 110 of the ATF1 gene was detected by reverse transcription-polymerase chain reaction. Because identical fusion of the FUS and ATF1 genes has been recently reported in another case of angiomatoid fibrous histiocytoma, fusion of these genes may be characteristic for at least a subset of these tumors.}},
author = {{Raddaoui, E and Donner, L and Panagopoulos, Ioannis}},
issn = {{1052-9551}},
keywords = {{molecular biology; ultrastructure; angiomatoid fibrous histiocytoma; immunohistochemistry; FUS gene; ATF1 gene}},
language = {{eng}},
number = {{3}},
pages = {{157--162}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Diagnostic Molecular Pathology}},
title = {{Fusion of the FUS and ATF1 genes in a large, deep-seated angiomatoid fibrous histiocytoma}},
url = {{http://www.molecularpathology.com/pt/re/dmp/abstract.00019606-200209000-00006.htm}},
volume = {{11}},
year = {{2002}},
}