SreC-dependent adaption to host iron environments regulates the transition of trophic stages and developmental processes of Curvularia lunata
(2024) In Molecular Plant Pathology 25(3).- Abstract
Plant pathogens are challenged by host-derived iron starvation or excess during infection, but the mechanism of plant pathogens rapidly adapting to the dynamic host iron environments to assimilate iron for invasion and colonization remains largely unexplored. Here, we found that the GATA transcription factor SreC in Curvularia lunata is required for virulence and adaption to the host iron excess environment. SreC directly binds to the ATGWGATAW element in an iron-dependent manner to regulate the switch between different iron assimilation pathways, conferring adaption to host iron environments in different trophic stages of C. lunata. SreC also regulates the transition of trophic stages and developmental processes in C. lunata.... (More)
Plant pathogens are challenged by host-derived iron starvation or excess during infection, but the mechanism of plant pathogens rapidly adapting to the dynamic host iron environments to assimilate iron for invasion and colonization remains largely unexplored. Here, we found that the GATA transcription factor SreC in Curvularia lunata is required for virulence and adaption to the host iron excess environment. SreC directly binds to the ATGWGATAW element in an iron-dependent manner to regulate the switch between different iron assimilation pathways, conferring adaption to host iron environments in different trophic stages of C. lunata. SreC also regulates the transition of trophic stages and developmental processes in C. lunata. SreC-dependent adaption to host iron environments is essential to the infectious growth and survival of C. lunata. We also demonstrate that CgSreA (a SreC orthologue) plays a similar role in Colletotrichum graminicola. We conclude that Sre mediates adaption to the host iron environment during infection, and the function is conserved in hemibiotrophic fungi.
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- author
- Sun, Jiaying ; Zhao, Jiamei ; Liu, Miaomiao ; Li, Jiayang ; Cheng, Jie ; Li, Wenling ; Yuan, Mingyue LU ; Xiao, Shuqin and Xue, Chunsheng
- organization
- publishing date
- 2024-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- GATA transcription factor SreC, hemibiotrophic fungi, host iron environment, iron assimilation pathways, trophic stage, virulence
- in
- Molecular Plant Pathology
- volume
- 25
- issue
- 3
- article number
- e13444
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:38481338
- scopus:85187762473
- ISSN
- 1464-6722
- DOI
- 10.1111/mpp.13444
- language
- English
- LU publication?
- yes
- id
- db81ee87-7f88-4c9b-9a7a-ba7059e7338b
- date added to LUP
- 2024-04-12 10:47:13
- date last changed
- 2024-04-19 10:10:45
@article{db81ee87-7f88-4c9b-9a7a-ba7059e7338b,
abstract = {{<p>Plant pathogens are challenged by host-derived iron starvation or excess during infection, but the mechanism of plant pathogens rapidly adapting to the dynamic host iron environments to assimilate iron for invasion and colonization remains largely unexplored. Here, we found that the GATA transcription factor SreC in Curvularia lunata is required for virulence and adaption to the host iron excess environment. SreC directly binds to the ATGWGATAW element in an iron-dependent manner to regulate the switch between different iron assimilation pathways, conferring adaption to host iron environments in different trophic stages of C. lunata. SreC also regulates the transition of trophic stages and developmental processes in C. lunata. SreC-dependent adaption to host iron environments is essential to the infectious growth and survival of C. lunata. We also demonstrate that CgSreA (a SreC orthologue) plays a similar role in Colletotrichum graminicola. We conclude that Sre mediates adaption to the host iron environment during infection, and the function is conserved in hemibiotrophic fungi.</p>}},
author = {{Sun, Jiaying and Zhao, Jiamei and Liu, Miaomiao and Li, Jiayang and Cheng, Jie and Li, Wenling and Yuan, Mingyue and Xiao, Shuqin and Xue, Chunsheng}},
issn = {{1464-6722}},
keywords = {{GATA transcription factor SreC; hemibiotrophic fungi; host iron environment; iron assimilation pathways; trophic stage; virulence}},
language = {{eng}},
number = {{3}},
publisher = {{Wiley-Blackwell}},
series = {{Molecular Plant Pathology}},
title = {{SreC-dependent adaption to host iron environments regulates the transition of trophic stages and developmental processes of Curvularia lunata}},
url = {{http://dx.doi.org/10.1111/mpp.13444}},
doi = {{10.1111/mpp.13444}},
volume = {{25}},
year = {{2024}},
}