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Naumovozyma castellii: an alternative model for budding yeast molecular biology

Cohn, Marita LU and Karademir Andersson, Ahu LU (2017) In Yeast 34(3). p.95-109
Abstract
Naumovozyma castellii (Saccharomyces castellii) is a member of the budding yeast family Saccharomycetaceae. It has been extensively used as a model organism for telomere biology research and has gained an increasing interest as a budding yeast model for functional analyses owing to its amenability to genetic modifications. Due to the suitable phylogenetic distance to S. cerevisiae the whole genome sequence of N. castellii has provided unique data for comparative genomic studies, and it played a key role in the establishment of the timing of the whole genome duplication and the evolutionary events that took place in the subsequent genomic evolution of the Saccharomyces lineage. Here we summarize the historical background of its... (More)
Naumovozyma castellii (Saccharomyces castellii) is a member of the budding yeast family Saccharomycetaceae. It has been extensively used as a model organism for telomere biology research and has gained an increasing interest as a budding yeast model for functional analyses owing to its amenability to genetic modifications. Due to the suitable phylogenetic distance to S. cerevisiae the whole genome sequence of N. castellii has provided unique data for comparative genomic studies, and it played a key role in the establishment of the timing of the whole genome duplication and the evolutionary events that took place in the subsequent genomic evolution of the Saccharomyces lineage. Here we summarize the historical background of its establishment as a laboratory yeast species, and the development of genetic and molecular tools and strains. We review the research performed on N. castellii, focusing on areas where it has significantly contributed to the discovery of new features of molecular biology and to the advancement of our understanding of molecular evolution.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
yeast, Genetics, Molecular Genetics, telomeres, centromeres, RNAi (RNA-interference), mitochondria, Genome evolution, mating system
in
Yeast
volume
34
issue
3
pages
15 pages
publisher
John Wiley & Sons
external identifiers
  • scopus:85006320817
  • wos:000398701200001
ISSN
1097-0061
DOI
10.1002/yea.3218
language
English
LU publication?
yes
id
dbe8a0c5-0a11-4da2-b1b0-57fdd5ea32c6
date added to LUP
2016-11-02 16:14:40
date last changed
2018-12-16 04:51:12
@article{dbe8a0c5-0a11-4da2-b1b0-57fdd5ea32c6,
  abstract     = {Naumovozyma castellii (Saccharomyces castellii) is a member of the budding yeast family Saccharomycetaceae. It has been extensively used as a model organism for telomere biology research and has gained an increasing interest as a budding yeast model for functional analyses owing to its amenability to genetic modifications. Due to the suitable phylogenetic distance to S. cerevisiae the whole genome sequence of N. castellii has provided unique data for comparative genomic studies, and it played a key role in the establishment of the timing of the whole genome duplication and the evolutionary events that took place in the subsequent genomic evolution of the Saccharomyces lineage. Here we summarize the historical background of its establishment as a laboratory yeast species, and the development of genetic and molecular tools and strains. We review the research performed on N. castellii, focusing on areas where it has significantly contributed to the discovery of new features of molecular biology and to the advancement of our understanding of molecular evolution.<br/>},
  author       = {Cohn, Marita and Karademir Andersson, Ahu},
  issn         = {1097-0061},
  keyword      = {yeast,Genetics,Molecular Genetics,telomeres,centromeres,RNAi (RNA-interference),mitochondria,Genome evolution,mating system},
  language     = {eng},
  number       = {3},
  pages        = {95--109},
  publisher    = {John Wiley & Sons},
  series       = {Yeast},
  title        = {Naumovozyma castellii: an alternative model for budding yeast molecular biology},
  url          = {http://dx.doi.org/10.1002/yea.3218},
  volume       = {34},
  year         = {2017},
}