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Forty years of successful national research collaboration in liver disease–the Swedish experience

Bergquist, Annika ; Ekstedt, Mattias ; Hagström, Hannes ; Järnerot, Gunnar ; Lindgren, Stefan LU ; Nilsson, Emma LU ; Nyhlin, Nils ; Rorsman, Fredrik ; Stål, Per and Werner, Mårten , et al. (2024) In Scandinavian Journal of Gastroenterology 59(12). p.1314-1321
Abstract

Aim: Sweden has historically provided a fruitful arena for research in clinical medicine. We here share 40 years of experience of collaboration in the Swedish hepatology research group (SWEHEP) (https://www.swehep.se). Methods: We describe the way the Swedish hepatology pioneers started the group and how the network continuously developed over the years. Successful projects such as thorough studies of natural history and various clinical aspects of autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and steatosis are described. Results: Over the years, more than 80 publications have been published by the group. A summary of new and ongoing research programs includes the randomized placebo-controlled trial... (More)

Aim: Sweden has historically provided a fruitful arena for research in clinical medicine. We here share 40 years of experience of collaboration in the Swedish hepatology research group (SWEHEP) (https://www.swehep.se). Methods: We describe the way the Swedish hepatology pioneers started the group and how the network continuously developed over the years. Successful projects such as thorough studies of natural history and various clinical aspects of autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and steatosis are described. Results: Over the years, more than 80 publications have been published by the group. A summary of new and ongoing research programs includes the randomized placebo-controlled trial of simvastatin in PSC (PiSCATIN), the prospective BIGMAP (Biochemical and genetic markers for the assessment and prognostication of liver cirrhosis) initiative in patients with liver cirrhosis, and the DETECT-HCC, a prospective multicenter cohort study comparing abbreviated MRI and ultrasound for surveillance of hepatocellular carcinoma every six months over two years. The group philosophy, success factors for the longstanding collaboration as well as experience of failures are shared. Conclusion: The success of hepatology research in Sweden is based on longstanding collaboration over generations of hepatologists, where everyone contributes, regular research meetings, mutual trust, and perseverance.

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author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
autoimmune hepatitis, cirrhosis, liver steatosis, primary biliary cholangitis, Primary sclerosing cholangitis
in
Scandinavian Journal of Gastroenterology
volume
59
issue
12
pages
8 pages
publisher
Taylor & Francis
external identifiers
  • pmid:39485016
  • scopus:85209191340
ISSN
0036-5521
DOI
10.1080/00365521.2024.2421824
language
English
LU publication?
yes
id
dd57b734-d656-4839-98ec-6162768c8a3a
date added to LUP
2025-02-17 10:37:46
date last changed
2025-07-07 22:16:58
@article{dd57b734-d656-4839-98ec-6162768c8a3a,
  abstract     = {{<p>Aim: Sweden has historically provided a fruitful arena for research in clinical medicine. We here share 40 years of experience of collaboration in the Swedish hepatology research group (SWEHEP) (https://www.swehep.se). Methods: We describe the way the Swedish hepatology pioneers started the group and how the network continuously developed over the years. Successful projects such as thorough studies of natural history and various clinical aspects of autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and steatosis are described. Results: Over the years, more than 80 publications have been published by the group. A summary of new and ongoing research programs includes the randomized placebo-controlled trial of simvastatin in PSC (PiSCATIN), the prospective BIGMAP (Biochemical and genetic markers for the assessment and prognostication of liver cirrhosis) initiative in patients with liver cirrhosis, and the DETECT-HCC, a prospective multicenter cohort study comparing abbreviated MRI and ultrasound for surveillance of hepatocellular carcinoma every six months over two years. The group philosophy, success factors for the longstanding collaboration as well as experience of failures are shared. Conclusion: The success of hepatology research in Sweden is based on longstanding collaboration over generations of hepatologists, where everyone contributes, regular research meetings, mutual trust, and perseverance.</p>}},
  author       = {{Bergquist, Annika and Ekstedt, Mattias and Hagström, Hannes and Järnerot, Gunnar and Lindgren, Stefan and Nilsson, Emma and Nyhlin, Nils and Rorsman, Fredrik and Stål, Per and Werner, Mårten and Kechagias, Stergios}},
  issn         = {{0036-5521}},
  keywords     = {{autoimmune hepatitis; cirrhosis; liver steatosis; primary biliary cholangitis; Primary sclerosing cholangitis}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1314--1321}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Gastroenterology}},
  title        = {{Forty years of successful national research collaboration in liver disease–the Swedish experience}},
  url          = {{http://dx.doi.org/10.1080/00365521.2024.2421824}},
  doi          = {{10.1080/00365521.2024.2421824}},
  volume       = {{59}},
  year         = {{2024}},
}