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Effectiveness of platelet-rich plasma in healing necrobiosis lipoidica diabeticorum ulcers

Motolese, A ; Vignati, F ; Antelmi, A LU and Saturni, V (2015) In Clinical and experimental dermatology 40(1). p.39-41
Abstract

Necrobiosis lipoidica diabeticorum (NLD) is a chronic condition, which is characterized by single or multiple lesions on the legs, and occurs in 0.3% of patients with diabetes. Recently, platelet-rich plasma (PRP) has been used in several clinical settings to promote sustained healing and better outcome. We propose the use of PRP for the treatment of NLD-associated recalcitrant wounds. In this study, 15 patients were treated with homologous PRP; all showed marked enhancement in wound healing without any adverse effects. After PRP application, advanced dressings were used until closure of the lesion was obtained, which was complete for all our patients. We therefore propose the use of PRP for recalcitrant wounds in patients with NLD.

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Aged, Bandages, Chronic Disease, Female, Humans, Leg Ulcer/therapy, Male, Middle Aged, Necrobiosis Lipoidica/therapy, Platelet-Rich Plasma
in
Clinical and experimental dermatology
volume
40
issue
1
pages
3 pages
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • scopus:84917673380
  • pmid:25266162
ISSN
0307-6938
DOI
10.1111/ced.12474
language
English
LU publication?
no
additional info
© 2014 British Association of Dermatologists.
id
dd99349d-465d-45c5-b9e2-3113d41529c4
date added to LUP
2019-07-23 15:42:08
date last changed
2020-10-20 04:57:56
@article{dd99349d-465d-45c5-b9e2-3113d41529c4,
  abstract     = {<p>Necrobiosis lipoidica diabeticorum (NLD) is a chronic condition, which is characterized by single or multiple lesions on the legs, and occurs in 0.3% of patients with diabetes. Recently, platelet-rich plasma (PRP) has been used in several clinical settings to promote sustained healing and better outcome. We propose the use of PRP for the treatment of NLD-associated recalcitrant wounds. In this study, 15 patients were treated with homologous PRP; all showed marked enhancement in wound healing without any adverse effects. After PRP application, advanced dressings were used until closure of the lesion was obtained, which was complete for all our patients. We therefore propose the use of PRP for recalcitrant wounds in patients with NLD. </p>},
  author       = {Motolese, A and Vignati, F and Antelmi, A and Saturni, V},
  issn         = {0307-6938},
  language     = {eng},
  number       = {1},
  pages        = {39--41},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Clinical and experimental dermatology},
  title        = {Effectiveness of platelet-rich plasma in healing necrobiosis lipoidica diabeticorum ulcers},
  url          = {http://dx.doi.org/10.1111/ced.12474},
  doi          = {10.1111/ced.12474},
  volume       = {40},
  year         = {2015},
}