Synthesis of Three-Dimensional Ring Fused Heterocycles by a Selective [4 + 2] Cycloaddition Between Bicyclic Thiazolo 2-Pyridones and Arynes
(2024) In Journal of Organic Chemistry 89(1). p.731-739- Abstract
A selective [4 + 2] cycloaddition reaction of thiazolo-2-pyridones with arynes has been demonstrated. The developed protocol allows rapid access to highly functionalized, structurally complex thiazolo-fused bridged isoquinolones in high yields, which are susceptible to further late-stage functionalization.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/ddccb1b4-0f80-4425-9444-25135210d892
- author
- Sarkar, Souvik ; Singh, Pardeep ; Edin, Simon LU ; Wendt, Ola F. LU and Almqvist, Fredrik
- organization
- publishing date
- 2024-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Organic Chemistry
- volume
- 89
- issue
- 1
- pages
- 9 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:38093677
- scopus:85180992605
- ISSN
- 0022-3263
- DOI
- 10.1021/acs.joc.3c01957
- language
- English
- LU publication?
- yes
- id
- ddccb1b4-0f80-4425-9444-25135210d892
- date added to LUP
- 2024-02-07 11:34:12
- date last changed
- 2024-04-23 18:20:11
@article{ddccb1b4-0f80-4425-9444-25135210d892, abstract = {{<p>A selective [4 + 2] cycloaddition reaction of thiazolo-2-pyridones with arynes has been demonstrated. The developed protocol allows rapid access to highly functionalized, structurally complex thiazolo-fused bridged isoquinolones in high yields, which are susceptible to further late-stage functionalization.</p>}}, author = {{Sarkar, Souvik and Singh, Pardeep and Edin, Simon and Wendt, Ola F. and Almqvist, Fredrik}}, issn = {{0022-3263}}, language = {{eng}}, number = {{1}}, pages = {{731--739}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Journal of Organic Chemistry}}, title = {{Synthesis of Three-Dimensional Ring Fused Heterocycles by a Selective [4 + 2] Cycloaddition Between Bicyclic Thiazolo 2-Pyridones and Arynes}}, url = {{http://dx.doi.org/10.1021/acs.joc.3c01957}}, doi = {{10.1021/acs.joc.3c01957}}, volume = {{89}}, year = {{2024}}, }