Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen
(2021) In Contact Dermatitis 85(6). p.660-670- Abstract
BACKGROUND: Contact allergy to fragrance mix I (FM I) is over-represented in patients photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I, cinnamal and cinnamyl alcohol, in ketoprofen-photoallergic patients is higher than in dermatitis patients.
OBJECTIVE: To explore the prevalence of contact allergy to FM I and its individual components in patients with photocontact allergy to ketoprofen, and to compare with a dermatitis and the general population.
METHODS: Data on patch and photopatch tests performed between 2009-2018 were collected. Ketoprofen-photoallergic patients were compared with dermatitis patients and published data on the general population regarding the prevalence and the... (More)
BACKGROUND: Contact allergy to fragrance mix I (FM I) is over-represented in patients photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I, cinnamal and cinnamyl alcohol, in ketoprofen-photoallergic patients is higher than in dermatitis patients.
OBJECTIVE: To explore the prevalence of contact allergy to FM I and its individual components in patients with photocontact allergy to ketoprofen, and to compare with a dermatitis and the general population.
METHODS: Data on patch and photopatch tests performed between 2009-2018 were collected. Ketoprofen-photoallergic patients were compared with dermatitis patients and published data on the general population regarding the prevalence and the distribution of contact allergy to FM I and its components.
RESULTS: A higher prevalence of contact allergy to cinnamyl alcohol compared to cinnamal (23.3% vs 10.0%), and eugenol compared to isoeugenol (23.3% vs 6.7%), was observed in ketoprofen-photoallergic patients, while the relationship was the opposite in dermatitis group (0.7% vs 1.05%; 0.4% vs 0.9%). Overall prevalence of contact allergy to several components of FM I was significantly higher in ketoprofen-photoallergic patients.
CONCLUSIONS: Contact allergy to FM I and many of its components is over-represented in patients photoallergic to ketoprofen compared to dermatitis patients and the general population. This article is protected by copyright. All rights reserved.
(Less)
- author
- Marmgren, Victoria LU ; Mowitz, Martin LU ; Zimerson, Erik LU ; Hindsén, Monica LU and Bruze, Magnus LU
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Contact Dermatitis
- volume
- 85
- issue
- 6
- pages
- 660 - 670
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:34414573
- scopus:85114332206
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.13958
- language
- English
- LU publication?
- yes
- id
- dde7076d-a544-435c-ae43-6f607fb1d860
- date added to LUP
- 2021-08-23 15:48:42
- date last changed
- 2024-06-15 15:07:13
@article{dde7076d-a544-435c-ae43-6f607fb1d860, abstract = {{<p>BACKGROUND: Contact allergy to fragrance mix I (FM I) is over-represented in patients photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I, cinnamal and cinnamyl alcohol, in ketoprofen-photoallergic patients is higher than in dermatitis patients.</p><p>OBJECTIVE: To explore the prevalence of contact allergy to FM I and its individual components in patients with photocontact allergy to ketoprofen, and to compare with a dermatitis and the general population.</p><p>METHODS: Data on patch and photopatch tests performed between 2009-2018 were collected. Ketoprofen-photoallergic patients were compared with dermatitis patients and published data on the general population regarding the prevalence and the distribution of contact allergy to FM I and its components.</p><p>RESULTS: A higher prevalence of contact allergy to cinnamyl alcohol compared to cinnamal (23.3% vs 10.0%), and eugenol compared to isoeugenol (23.3% vs 6.7%), was observed in ketoprofen-photoallergic patients, while the relationship was the opposite in dermatitis group (0.7% vs 1.05%; 0.4% vs 0.9%). Overall prevalence of contact allergy to several components of FM I was significantly higher in ketoprofen-photoallergic patients.</p><p>CONCLUSIONS: Contact allergy to FM I and many of its components is over-represented in patients photoallergic to ketoprofen compared to dermatitis patients and the general population. This article is protected by copyright. All rights reserved.</p>}}, author = {{Marmgren, Victoria and Mowitz, Martin and Zimerson, Erik and Hindsén, Monica and Bruze, Magnus}}, issn = {{0105-1873}}, language = {{eng}}, number = {{6}}, pages = {{660--670}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen}}, url = {{http://dx.doi.org/10.1111/cod.13958}}, doi = {{10.1111/cod.13958}}, volume = {{85}}, year = {{2021}}, }