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Mitophagy : A Mechanism for Plant Growth and Survival

Broda, Martyna; Millar, A. Harvey and Van Aken, Olivier LU (2018) In Trends in Plant Science 23(5). p.434-450
Abstract

Mitophagy is a conserved cellular process that is important for autophagic removal of damaged mitochondria to maintain a healthy mitochondrial population. Mitophagy also appears to occur in plants and has roles in development, stress response, senescence, and programmed cell death. However, many of the genes that control mitophagy in yeast and animal cells are absent from plants, and no plant proteins marking defunct mitochondria for autophagic degradation are yet known. New insights implicate general autophagy-related proteins in mitophagy, affecting the senescence of plant tissues. Mitophagy control and its importance for energy metabolism, survival, signaling, and cell death in plants are discussed. Furthermore, we suggest... (More)

Mitophagy is a conserved cellular process that is important for autophagic removal of damaged mitochondria to maintain a healthy mitochondrial population. Mitophagy also appears to occur in plants and has roles in development, stress response, senescence, and programmed cell death. However, many of the genes that control mitophagy in yeast and animal cells are absent from plants, and no plant proteins marking defunct mitochondria for autophagic degradation are yet known. New insights implicate general autophagy-related proteins in mitophagy, affecting the senescence of plant tissues. Mitophagy control and its importance for energy metabolism, survival, signaling, and cell death in plants are discussed. Furthermore, we suggest mitochondrial membrane proteins containing ATG8-interacting motifs, which might serve as mitophagy receptor proteins in plant mitochondria.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
autophagy, cell death, mitochondria, plant hormones, reactive oxygen species, senescence
in
Trends in Plant Science
volume
23
issue
5
pages
434 - 450
publisher
Elsevier
external identifiers
  • scopus:85044310533
ISSN
1360-1385
DOI
10.1016/j.tplants.2018.02.010
language
English
LU publication?
yes
id
df6dcd25-1b3d-4de0-8d4b-bee2de13a1f8
date added to LUP
2018-04-10 06:51:11
date last changed
2019-10-15 06:35:00
@article{df6dcd25-1b3d-4de0-8d4b-bee2de13a1f8,
  abstract     = {<p>Mitophagy is a conserved cellular process that is important for autophagic removal of damaged mitochondria to maintain a healthy mitochondrial population. Mitophagy also appears to occur in plants and has roles in development, stress response, senescence, and programmed cell death. However, many of the genes that control mitophagy in yeast and animal cells are absent from plants, and no plant proteins marking defunct mitochondria for autophagic degradation are yet known. New insights implicate general autophagy-related proteins in mitophagy, affecting the senescence of plant tissues. Mitophagy control and its importance for energy metabolism, survival, signaling, and cell death in plants are discussed. Furthermore, we suggest mitochondrial membrane proteins containing ATG8-interacting motifs, which might serve as mitophagy receptor proteins in plant mitochondria.</p>},
  author       = {Broda, Martyna and Millar, A. Harvey and Van Aken, Olivier},
  issn         = {1360-1385},
  keyword      = {autophagy,cell death,mitochondria,plant hormones,reactive oxygen species,senescence},
  language     = {eng},
  number       = {5},
  pages        = {434--450},
  publisher    = {Elsevier},
  series       = {Trends in Plant Science},
  title        = {Mitophagy : A Mechanism for Plant Growth and Survival},
  url          = {http://dx.doi.org/10.1016/j.tplants.2018.02.010},
  volume       = {23},
  year         = {2018},
}