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In vivo dose verification of IMRT treated head and neck cancer patients

Engström, Per E LU ; Haraldsson, Pia; Landberg, Torsten LU ; Sand Hansen, Hanne; Aage Engelholm, Svend and Nyström, Håkan (2005) In Acta oncologica (Stockholm, Sweden) 44(6). p.8-572
Abstract

An independent in vivo dose verification procedure for IMRT treatments of head and neck cancers was developed. Results of 177 intracavitary TLD measurements from 10 patients are presented. The study includes data from 10 patients with cancer of the rhinopharynx or the thyroid treated with dynamic IMRT. Dose verification was performed by insertion of a flexible naso-oesophageal tube containing TLD rods and markers for EPID and simulator image detection. Part of the study focussed on investigating the accuracy of the TPS calculations in the presence of inhomogeneities. Phantom measurements and Monte Carlo simulations were performed for a number of geometries involving lateral electronic disequilibrium and steep density shifts. The in vivo... (More)

An independent in vivo dose verification procedure for IMRT treatments of head and neck cancers was developed. Results of 177 intracavitary TLD measurements from 10 patients are presented. The study includes data from 10 patients with cancer of the rhinopharynx or the thyroid treated with dynamic IMRT. Dose verification was performed by insertion of a flexible naso-oesophageal tube containing TLD rods and markers for EPID and simulator image detection. Part of the study focussed on investigating the accuracy of the TPS calculations in the presence of inhomogeneities. Phantom measurements and Monte Carlo simulations were performed for a number of geometries involving lateral electronic disequilibrium and steep density shifts. The in vivo TLD measurements correlated well with the predictions of the treatment planning system with a measured/calculated dose ratio of 1.002+/-0.051 (1 SD, N=177). The measurements were easily performed and well tolerated by the patients. We conclude that in vivo intracavitary dosimetry with TLD is suitable and accurate for dose determination in intensity-modulated beams.

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publishing date
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Contribution to journal
publication status
published
keywords
Algorithms, Computer Simulation, Humans, Models, Biological, Monte Carlo Method, Nasopharyngeal Neoplasms, Phantoms, Imaging, Radiation Dosage, Radiometry, Radiotherapy Planning, Computer-Assisted, Radiotherapy, Intensity-Modulated, Reproducibility of Results, Thermoluminescent Dosimetry, Thyroid Neoplasms, Comparative Study, Journal Article
in
Acta oncologica (Stockholm, Sweden)
volume
44
issue
6
pages
7 pages
publisher
Taylor & Francis
external identifiers
  • scopus:27144443330
ISSN
0284-186X
DOI
10.1080/02841860500218983
language
English
LU publication?
no
id
e151ba25-92c4-4bbe-bcd7-90673f19ac57
date added to LUP
2018-03-01 15:18:24
date last changed
2018-05-29 11:55:05
@article{e151ba25-92c4-4bbe-bcd7-90673f19ac57,
  abstract     = {<p>An independent in vivo dose verification procedure for IMRT treatments of head and neck cancers was developed. Results of 177 intracavitary TLD measurements from 10 patients are presented. The study includes data from 10 patients with cancer of the rhinopharynx or the thyroid treated with dynamic IMRT. Dose verification was performed by insertion of a flexible naso-oesophageal tube containing TLD rods and markers for EPID and simulator image detection. Part of the study focussed on investigating the accuracy of the TPS calculations in the presence of inhomogeneities. Phantom measurements and Monte Carlo simulations were performed for a number of geometries involving lateral electronic disequilibrium and steep density shifts. The in vivo TLD measurements correlated well with the predictions of the treatment planning system with a measured/calculated dose ratio of 1.002+/-0.051 (1 SD, N=177). The measurements were easily performed and well tolerated by the patients. We conclude that in vivo intracavitary dosimetry with TLD is suitable and accurate for dose determination in intensity-modulated beams.</p>},
  author       = {Engström, Per E and Haraldsson, Pia and Landberg, Torsten and Sand Hansen, Hanne and Aage Engelholm, Svend and Nyström, Håkan},
  issn         = {0284-186X},
  keyword      = {Algorithms,Computer Simulation,Humans,Models, Biological,Monte Carlo Method,Nasopharyngeal Neoplasms,Phantoms, Imaging,Radiation Dosage,Radiometry,Radiotherapy Planning, Computer-Assisted,Radiotherapy, Intensity-Modulated,Reproducibility of Results,Thermoluminescent Dosimetry,Thyroid Neoplasms,Comparative Study,Journal Article},
  language     = {eng},
  number       = {6},
  pages        = {8--572},
  publisher    = {Taylor & Francis},
  series       = {Acta oncologica (Stockholm, Sweden)},
  title        = {In vivo dose verification of IMRT treated head and neck cancer patients},
  url          = {http://dx.doi.org/10.1080/02841860500218983},
  volume       = {44},
  year         = {2005},
}