Field-hybridization acoustic tweezers
(2025) In Physical Review Applied 23(1).- Abstract
Precise control of individual particles is crucial for biomedical diagnostics, i.e., single-cell analysis and drug delivery. Acoustic tweezers have shown promise as a precise method for capturing microscale objects, but the spatial selectivity remains challenging to achieve with traditional electroacoustic transducers. An alternative to traditional ultrasound generation is to use photoacoustic conversion from laser pulses, allowing easy customization of acoustic field using optical light patterns, but this approach suffers from low efficiency of photoacoustic conversion. Here, we propose a field-hybridization technique to combine a hologram-generated photoacoustic field with a high-power featureless electroacoustic field. Theoretical... (More)
Precise control of individual particles is crucial for biomedical diagnostics, i.e., single-cell analysis and drug delivery. Acoustic tweezers have shown promise as a precise method for capturing microscale objects, but the spatial selectivity remains challenging to achieve with traditional electroacoustic transducers. An alternative to traditional ultrasound generation is to use photoacoustic conversion from laser pulses, allowing easy customization of acoustic field using optical light patterns, but this approach suffers from low efficiency of photoacoustic conversion. Here, we propose a field-hybridization technique to combine a hologram-generated photoacoustic field with a high-power featureless electroacoustic field. Theoretical and experimental validation show that while the force remains limited to the low pN range, the hybridization amplifies the photoacoustic radiation force by a factor of 80. By adjusting phase difference between electroacoustic and photoacoustic sources, the direction of particle motion can be reversed. The maximum trapping force is reached within 40 μm from the laser spot, which suggests that the method could enable highly precise and selective manipulation.
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- author
- Wang, Qing LU ; Chen, Shuhan ; Zhou, Jia and Riaud, Antoine
- organization
- publishing date
- 2025-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physical Review Applied
- volume
- 23
- issue
- 1
- article number
- 014049
- publisher
- American Physical Society
- external identifiers
-
- scopus:85215942706
- ISSN
- 2331-7019
- DOI
- 10.1103/PhysRevApplied.23.014049
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2025 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the "https://creativecommons.org/licenses/by/4.0/"Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Funded by "https://www.kb.se/samverkan-och-utveckling/oppen-tillgang-och-bibsamkonsortiet/bibsamkonsortiet.html"Bibsam.
- id
- e1938a8a-bdba-49d2-9de1-0f6f0e0b4435
- date added to LUP
- 2025-04-22 10:54:02
- date last changed
- 2025-04-22 10:55:24
@article{e1938a8a-bdba-49d2-9de1-0f6f0e0b4435,
abstract = {{<p>Precise control of individual particles is crucial for biomedical diagnostics, i.e., single-cell analysis and drug delivery. Acoustic tweezers have shown promise as a precise method for capturing microscale objects, but the spatial selectivity remains challenging to achieve with traditional electroacoustic transducers. An alternative to traditional ultrasound generation is to use photoacoustic conversion from laser pulses, allowing easy customization of acoustic field using optical light patterns, but this approach suffers from low efficiency of photoacoustic conversion. Here, we propose a field-hybridization technique to combine a hologram-generated photoacoustic field with a high-power featureless electroacoustic field. Theoretical and experimental validation show that while the force remains limited to the low pN range, the hybridization amplifies the photoacoustic radiation force by a factor of 80. By adjusting phase difference between electroacoustic and photoacoustic sources, the direction of particle motion can be reversed. The maximum trapping force is reached within 40 μm from the laser spot, which suggests that the method could enable highly precise and selective manipulation.</p>}},
author = {{Wang, Qing and Chen, Shuhan and Zhou, Jia and Riaud, Antoine}},
issn = {{2331-7019}},
language = {{eng}},
number = {{1}},
publisher = {{American Physical Society}},
series = {{Physical Review Applied}},
title = {{Field-hybridization acoustic tweezers}},
url = {{http://dx.doi.org/10.1103/PhysRevApplied.23.014049}},
doi = {{10.1103/PhysRevApplied.23.014049}},
volume = {{23}},
year = {{2025}},
}