Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Hepatic venous outflow reconstruction in right live donor liver transplantation

Malago, Massimo ; Molmenti, Ernesto P ; Paul, Andreas ; Nadalin, Silvio ; Lang, Hauke ; Radtke, Arnold ; Liu, Chao ; Frilling, Andrea ; Biglarnia, Reza LU orcid and Broelsch, Christoph E (2005) In Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 11(3). p.5-364
Abstract

The increasing experience with live donor liver transplantation has allowed for the identification of potential morbidities associated with technical considerations. Technical graft failure can be associated with both inflow and outflow vascular compromise. Although the latter has not always been given the relevance of the former, evidence pointing to its pivotal role continues to mount. We believe that impaired venous outflow was a cause of previously unexplained graft failures during our initial experience. Based on this observation, we developed a technique to prevent the "choking" of the graft at the outflow anastomosis with the inferior vena cava (IVC). The enhanced outflow via a cloaca maximum is achieved by reconstructing the... (More)

The increasing experience with live donor liver transplantation has allowed for the identification of potential morbidities associated with technical considerations. Technical graft failure can be associated with both inflow and outflow vascular compromise. Although the latter has not always been given the relevance of the former, evidence pointing to its pivotal role continues to mount. We believe that impaired venous outflow was a cause of previously unexplained graft failures during our initial experience. Based on this observation, we developed a technique to prevent the "choking" of the graft at the outflow anastomosis with the inferior vena cava (IVC). The enhanced outflow via a cloaca maximum is achieved by reconstructing the graft vessels with preserved veins or arteries (usually iliac vessels are used) from a blood-group-identical or blood-group-compatible deceased organ donor. Alternatively, hepatic vein or portal vein obtained from the resected native liver can be used. The reconstructed common outflow is anastomosed to a triangular opening of the IVC. Such enhanced outflow provides optimal venous drainage, especially during the early phase of growth of the graft.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Anastomosis, Surgical, Hepatectomy/methods, Hepatic Veins/surgery, Humans, Liver Transplantation/methods, Living Donors, Plastic Surgery Procedures/methods, Tissue and Organ Harvesting/methods
in
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
volume
11
issue
3
pages
5 - 364
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:15719402
  • scopus:20144389067
ISSN
1527-6465
DOI
10.1002/lt.20369
language
English
LU publication?
no
id
e1cba7ec-5b32-4d10-a396-75771a146d0f
date added to LUP
2025-12-17 14:24:58
date last changed
2025-12-19 02:25:42
@article{e1cba7ec-5b32-4d10-a396-75771a146d0f,
  abstract     = {{<p>The increasing experience with live donor liver transplantation has allowed for the identification of potential morbidities associated with technical considerations. Technical graft failure can be associated with both inflow and outflow vascular compromise. Although the latter has not always been given the relevance of the former, evidence pointing to its pivotal role continues to mount. We believe that impaired venous outflow was a cause of previously unexplained graft failures during our initial experience. Based on this observation, we developed a technique to prevent the "choking" of the graft at the outflow anastomosis with the inferior vena cava (IVC). The enhanced outflow via a cloaca maximum is achieved by reconstructing the graft vessels with preserved veins or arteries (usually iliac vessels are used) from a blood-group-identical or blood-group-compatible deceased organ donor. Alternatively, hepatic vein or portal vein obtained from the resected native liver can be used. The reconstructed common outflow is anastomosed to a triangular opening of the IVC. Such enhanced outflow provides optimal venous drainage, especially during the early phase of growth of the graft.</p>}},
  author       = {{Malago, Massimo and Molmenti, Ernesto P and Paul, Andreas and Nadalin, Silvio and Lang, Hauke and Radtke, Arnold and Liu, Chao and Frilling, Andrea and Biglarnia, Reza and Broelsch, Christoph E}},
  issn         = {{1527-6465}},
  keywords     = {{Anastomosis, Surgical; Hepatectomy/methods; Hepatic Veins/surgery; Humans; Liver Transplantation/methods; Living Donors; Plastic Surgery Procedures/methods; Tissue and Organ Harvesting/methods}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{5--364}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society}},
  title        = {{Hepatic venous outflow reconstruction in right live donor liver transplantation}},
  url          = {{http://dx.doi.org/10.1002/lt.20369}},
  doi          = {{10.1002/lt.20369}},
  volume       = {{11}},
  year         = {{2005}},
}