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Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities

Ingemarsson, Ingemar LU ; Herbst, Andreas LU and Thorngren-Jerneck, Kristina LU (1997) In British Journal of Obstetrics and Gynaecology 104(10). p.1123-1127
Abstract
OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more... (More)
OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH < 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Obstetrics and Gynaecology
volume
104
issue
10
pages
1123 - 1127
publisher
Wiley-Blackwell
external identifiers
  • pmid:9332988
  • scopus:0030924044
ISSN
1365-215X
DOI
10.1111/j.1471-0528.1997.tb10934.x
language
English
LU publication?
yes
id
e2682c7e-2efa-49d0-8b90-03923962de68 (old id 1111468)
date added to LUP
2016-04-01 12:34:26
date last changed
2025-10-14 11:12:22
@article{e2682c7e-2efa-49d0-8b90-03923962de68,
  abstract     = {{OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH &lt; 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH &gt; 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH &lt; 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH &lt; 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome.}},
  author       = {{Ingemarsson, Ingemar and Herbst, Andreas and Thorngren-Jerneck, Kristina}},
  issn         = {{1365-215X}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{1123--1127}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{British Journal of Obstetrics and Gynaecology}},
  title        = {{Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities}},
  url          = {{http://dx.doi.org/10.1111/j.1471-0528.1997.tb10934.x}},
  doi          = {{10.1111/j.1471-0528.1997.tb10934.x}},
  volume       = {{104}},
  year         = {{1997}},
}