Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Mammogram registration : A phantom-based evaluation of compressed breast thickness variation effects

Richard, Frédéric J.P. ; Bakić, Predrag R. LU and Maidment, Andrew D.A. (2006) In IEEE Transactions on Medical Imaging 25(2). p.188-197
Abstract

The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinical mammograms. In this paper, we propose a systematic approach to evaluate sensitivity of registration methods to various types of changes in mammograms using synthetic breast images with known deformations. As a first step, images of the same simulated breasts with various amounts of simulated physical compression have been used to evaluate a... (More)

The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinical mammograms. In this paper, we propose a systematic approach to evaluate sensitivity of registration methods to various types of changes in mammograms using synthetic breast images with known deformations. As a first step, images of the same simulated breasts with various amounts of simulated physical compression have been used to evaluate a previously described nonrigid mammogram registration technique. Registration performance is measured by calculating the average displacement error over a set of evaluation points identified in mammogram pairs. Applying appropriate thickness compensation and using a preferred order of the registered images, we obtained an average displacement error of 1.6 mm for mammograms with compression differences of 1-3 cm. The proposed methodology is applicable to analysis of other sources of mammogram differences and can be extended to the registration of multimodality breast data.

(Less)
Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Breast compression, Evaluation, Finite elements, Image registration, Mammogram synthesis, Mammography, Multi-grid optimization, Partial differential equations, Tissue modeling
in
IEEE Transactions on Medical Imaging
volume
25
issue
2
pages
10 pages
publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • pmid:16468453
  • scopus:31644431957
ISSN
0278-0062
DOI
10.1109/TMI.2005.862204
language
English
LU publication?
no
id
e2fa97ab-9425-4120-894e-55b7a3ab3135
date added to LUP
2020-11-07 13:20:03
date last changed
2024-01-02 21:18:07
@article{e2fa97ab-9425-4120-894e-55b7a3ab3135,
  abstract     = {{<p>The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinical mammograms. In this paper, we propose a systematic approach to evaluate sensitivity of registration methods to various types of changes in mammograms using synthetic breast images with known deformations. As a first step, images of the same simulated breasts with various amounts of simulated physical compression have been used to evaluate a previously described nonrigid mammogram registration technique. Registration performance is measured by calculating the average displacement error over a set of evaluation points identified in mammogram pairs. Applying appropriate thickness compensation and using a preferred order of the registered images, we obtained an average displacement error of 1.6 mm for mammograms with compression differences of 1-3 cm. The proposed methodology is applicable to analysis of other sources of mammogram differences and can be extended to the registration of multimodality breast data.</p>}},
  author       = {{Richard, Frédéric J.P. and Bakić, Predrag R. and Maidment, Andrew D.A.}},
  issn         = {{0278-0062}},
  keywords     = {{Breast compression; Evaluation; Finite elements; Image registration; Mammogram synthesis; Mammography; Multi-grid optimization; Partial differential equations; Tissue modeling}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{188--197}},
  publisher    = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}},
  series       = {{IEEE Transactions on Medical Imaging}},
  title        = {{Mammogram registration : A phantom-based evaluation of compressed breast thickness variation effects}},
  url          = {{http://dx.doi.org/10.1109/TMI.2005.862204}},
  doi          = {{10.1109/TMI.2005.862204}},
  volume       = {{25}},
  year         = {{2006}},
}