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Atypisk subakut tyreoidit gav differentialdiagnostiska problem : Ovanligt fall av graves tyreotoxikos i kombination med subakut tyreoidit med atypisk klinisk bild

Koutouridou, Emmanouela ; Planck, Tereza LU ; Uddman, Erik LU and Lantz, Mikael (2018) In Lakartidningen 115(16).
Abstract

Subacute thyroiditis is a common inflammatory disorder of the thyroid gland, possibly of viral etiology, that typically presents with neck pain, fever and tenderness on palpation of the thyroid gland. Graves’ disease is an autoimmune thyroid disorder caused by stimulation of the thyroid gland by thyrotropin receptor antibodies (TRAb). The development of Graves´ disease and subacute thyroiditis simultaneously is an uncommon condition and only a few cases have been reported. In this article we present a case of a 46-year old woman diagnosed with Graves´ disease who was started on thiamazole and weeks later developed high fever. Several differential diagnoses were considered such as infection, lymphoma and vasculitis due to thiamazole.... (More)

Subacute thyroiditis is a common inflammatory disorder of the thyroid gland, possibly of viral etiology, that typically presents with neck pain, fever and tenderness on palpation of the thyroid gland. Graves’ disease is an autoimmune thyroid disorder caused by stimulation of the thyroid gland by thyrotropin receptor antibodies (TRAb). The development of Graves´ disease and subacute thyroiditis simultaneously is an uncommon condition and only a few cases have been reported. In this article we present a case of a 46-year old woman diagnosed with Graves´ disease who was started on thiamazole and weeks later developed high fever. Several differential diagnoses were considered such as infection, lymphoma and vasculitis due to thiamazole. Finally, the fine needle aspiration of the thyroid gland displayed histopathological features of subacute thyroiditis. Remarkably, our patient did not have neck pain or tenderness on palpation of the thyroid gland and overall the clinical presentation of subacute thyroiditis was atypical. Thus, subacute thyroiditis may be considered as a potential cause of fever of unknown origin.

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author
organization
alternative title
Atypical subacute thyroiditis in combination with grave’s disease : Diagnostic difficulties in a case report
publishing date
type
Contribution to journal
publication status
published
subject
in
Lakartidningen
volume
115
issue
16
pages
1 pages
publisher
Swedish Medical Association
external identifiers
  • scopus:85045611908
ISSN
0023-7205
language
Swedish
LU publication?
no
id
e415b932-5780-4075-8df6-742ed038f9be
date added to LUP
2018-05-04 13:00:32
date last changed
2020-01-13 00:41:00
@article{e415b932-5780-4075-8df6-742ed038f9be,
  abstract     = {<p>Subacute thyroiditis is a common inflammatory disorder of the thyroid gland, possibly of viral etiology, that typically presents with neck pain, fever and tenderness on palpation of the thyroid gland. Graves’ disease is an autoimmune thyroid disorder caused by stimulation of the thyroid gland by thyrotropin receptor antibodies (TRAb). The development of Graves´ disease and subacute thyroiditis simultaneously is an uncommon condition and only a few cases have been reported. In this article we present a case of a 46-year old woman diagnosed with Graves´ disease who was started on thiamazole and weeks later developed high fever. Several differential diagnoses were considered such as infection, lymphoma and vasculitis due to thiamazole. Finally, the fine needle aspiration of the thyroid gland displayed histopathological features of subacute thyroiditis. Remarkably, our patient did not have neck pain or tenderness on palpation of the thyroid gland and overall the clinical presentation of subacute thyroiditis was atypical. Thus, subacute thyroiditis may be considered as a potential cause of fever of unknown origin.</p>},
  author       = {Koutouridou, Emmanouela and Planck, Tereza and Uddman, Erik and Lantz, Mikael},
  issn         = {0023-7205},
  language     = {swe},
  month        = {01},
  number       = {16},
  publisher    = {Swedish Medical Association},
  series       = {Lakartidningen},
  title        = {Atypisk subakut tyreoidit gav differentialdiagnostiska problem : Ovanligt fall av graves tyreotoxikos i kombination med subakut tyreoidit med atypisk klinisk bild},
  volume       = {115},
  year         = {2018},
}