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Refractive error and glaucoma

Grødum, Kirsti LU ; Heijl, Anders LU and Bengtsson, B. Bo LU (2001) In Acta Ophthalmologica Scandinavica 79(6). p.560-566
Abstract

Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population. Methods: We examined 32,918 citizens of the city of Malmö, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 program. Results: Glaucoma prevalence was clearly associated with refractive state, increasing gradually with increasing myopia. This was seen both in males and females and persisted over the full age range. Glaucoma was significantly more common in myopic than in hyperopic eyes with low IOP readings (p=0.024). The overrpresentation of glaucoma in... (More)

Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population. Methods: We examined 32,918 citizens of the city of Malmö, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 program. Results: Glaucoma prevalence was clearly associated with refractive state, increasing gradually with increasing myopia. This was seen both in males and females and persisted over the full age range. Glaucoma was significantly more common in myopic than in hyperopic eyes with low IOP readings (p=0.024). The overrpresentation of glaucoma in myopic eyes declined with increasing IOP and no relationship was observed in eyes with IOP ≥31 mmHg. Conclusion: In this large population, the prevalence of glaucoma increased with increasing myopia. The association between myopia and glaucoma was strong at lower IOP levels, and weakened gradually with increasing IOP. Our findings indicate that myopia is an important risk factor for glaucoma and particularly for normal tension glaucoma.

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author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Glaucoma, Intraocular pressure, Myopia, Refractive error
in
Acta Ophthalmologica Scandinavica
volume
79
issue
6
pages
7 pages
publisher
Wiley
external identifiers
  • scopus:0035207286
  • pmid:11782219
ISSN
1395-3907
DOI
10.1034/j.1600-0420.2001.790603.x
language
English
LU publication?
no
id
e4185202-c51f-4a8d-83d2-30893ab3f68a
date added to LUP
2019-06-27 20:33:51
date last changed
2024-04-16 14:10:02
@article{e4185202-c51f-4a8d-83d2-30893ab3f68a,
  abstract     = {{<p>Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population. Methods: We examined 32,918 citizens of the city of Malmö, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 program. Results: Glaucoma prevalence was clearly associated with refractive state, increasing gradually with increasing myopia. This was seen both in males and females and persisted over the full age range. Glaucoma was significantly more common in myopic than in hyperopic eyes with low IOP readings (p=0.024). The overrpresentation of glaucoma in myopic eyes declined with increasing IOP and no relationship was observed in eyes with IOP ≥31 mmHg. Conclusion: In this large population, the prevalence of glaucoma increased with increasing myopia. The association between myopia and glaucoma was strong at lower IOP levels, and weakened gradually with increasing IOP. Our findings indicate that myopia is an important risk factor for glaucoma and particularly for normal tension glaucoma.</p>}},
  author       = {{Grødum, Kirsti and Heijl, Anders and Bengtsson, B. Bo}},
  issn         = {{1395-3907}},
  keywords     = {{Glaucoma; Intraocular pressure; Myopia; Refractive error}},
  language     = {{eng}},
  month        = {{12}},
  number       = {{6}},
  pages        = {{560--566}},
  publisher    = {{Wiley}},
  series       = {{Acta Ophthalmologica Scandinavica}},
  title        = {{Refractive error and glaucoma}},
  url          = {{http://dx.doi.org/10.1034/j.1600-0420.2001.790603.x}},
  doi          = {{10.1034/j.1600-0420.2001.790603.x}},
  volume       = {{79}},
  year         = {{2001}},
}