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A high-repetition rate scheme for synchrotron-based picosecond laser pumpx-ray probe experiments on chemical and biological systems in solution

Lima, Frederico A. ; Milne, Christopher J. ; Amarasinghe, Dimali C.V. ; Rittmann-Frank, Mercedes Hannelore ; Veen, Renske M.Van Der ; Reinhard, Marco ; Karlsson, Susanne ; Johnson, Steven L. ; Grolimund, Daniel and Borca, Camelia , et al. (2011) In Review of Scientific Instruments 82(6).
Abstract

We present the extension of time-resolved optical pump/x-ray absorption spectroscopy (XAS) probe experiments towards data collection at MHz repetition rates. The use of a high-power picosecond laser operating at an integer fraction of the repetition rate of the storage ring allows exploitation of up to two orders of magnitude more x-ray photons than in previous schemes based on the use of kHz lasers. Consequently, we demonstrate an order of magnitude increase in the signal-to-noise of time-resolved XAS of molecular systems in solution. This makes it possible to investigate highly dilute samples at concentrations approaching physiological conditions for biological systems. The simplicity and compactness of the scheme allows for... (More)

We present the extension of time-resolved optical pump/x-ray absorption spectroscopy (XAS) probe experiments towards data collection at MHz repetition rates. The use of a high-power picosecond laser operating at an integer fraction of the repetition rate of the storage ring allows exploitation of up to two orders of magnitude more x-ray photons than in previous schemes based on the use of kHz lasers. Consequently, we demonstrate an order of magnitude increase in the signal-to-noise of time-resolved XAS of molecular systems in solution. This makes it possible to investigate highly dilute samples at concentrations approaching physiological conditions for biological systems. The simplicity and compactness of the scheme allows for straightforward implementation at any synchrotron beamline and for a wide range of x-ray probe techniques, such as time-resolved diffraction or x-ray emission studies.

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publishing date
type
Contribution to journal
publication status
published
subject
in
Review of Scientific Instruments
volume
82
issue
6
article number
063111
publisher
American Institute of Physics (AIP)
external identifiers
  • scopus:79960167262
  • pmid:21721678
ISSN
0034-6748
DOI
10.1063/1.3600616
language
English
LU publication?
no
id
e48ee94a-5e11-402e-b778-e9439d8ac910
date added to LUP
2019-06-30 09:52:22
date last changed
2021-02-17 07:18:48
@article{e48ee94a-5e11-402e-b778-e9439d8ac910,
  abstract     = {<p>We present the extension of time-resolved optical pump/x-ray absorption spectroscopy (XAS) probe experiments towards data collection at MHz repetition rates. The use of a high-power picosecond laser operating at an integer fraction of the repetition rate of the storage ring allows exploitation of up to two orders of magnitude more x-ray photons than in previous schemes based on the use of kHz lasers. Consequently, we demonstrate an order of magnitude increase in the signal-to-noise of time-resolved XAS of molecular systems in solution. This makes it possible to investigate highly dilute samples at concentrations approaching physiological conditions for biological systems. The simplicity and compactness of the scheme allows for straightforward implementation at any synchrotron beamline and for a wide range of x-ray probe techniques, such as time-resolved diffraction or x-ray emission studies.</p>},
  author       = {Lima, Frederico A. and Milne, Christopher J. and Amarasinghe, Dimali C.V. and Rittmann-Frank, Mercedes Hannelore and Veen, Renske M.Van Der and Reinhard, Marco and Karlsson, Susanne and Johnson, Steven L. and Grolimund, Daniel and Borca, Camelia and Huthwelker, Thomas and Janousch, Markus and Van Mourik, Frank and Abela, Rafael and Chergui, Majed},
  issn         = {0034-6748},
  language     = {eng},
  number       = {6},
  publisher    = {American Institute of Physics (AIP)},
  series       = {Review of Scientific Instruments},
  title        = {A high-repetition rate scheme for synchrotron-based picosecond laser pumpx-ray probe experiments on chemical and biological systems in solution},
  url          = {http://dx.doi.org/10.1063/1.3600616},
  doi          = {10.1063/1.3600616},
  volume       = {82},
  year         = {2011},
}