Feminization of complex traits in Drosophila melanogaster via female-limited X chromosome evolution
Lund-Hansen, Katrine K. LU
; Abbott, Jessica K.
LU
and Morrow, Edward H.
(2020)
In Evolution
74(12).
p.2703-2713
- Abstract
A handful of studies have investigated sexually antagonistic constraints on achieving sex-specific fitness optima, although exclusively through male-genome-limited evolution experiments. In this article, we established a female-limited X chromosome evolution experiment, where we used an X chromosome balancer to enforce the inheritance of the X through the matriline, thus removing exposure to male selective constraints. This approach eliminates the effects of sexually antagonistic selection on the X chromosome, permitting evolution toward a single sex-specific optimum. After multiple generations of selection, we found strong evidence that body size and development time had moved toward a female-specific optimum, whereas reproductive... (More)
A handful of studies have investigated sexually antagonistic constraints on achieving sex-specific fitness optima, although exclusively through male-genome-limited evolution experiments. In this article, we established a female-limited X chromosome evolution experiment, where we used an X chromosome balancer to enforce the inheritance of the X through the matriline, thus removing exposure to male selective constraints. This approach eliminates the effects of sexually antagonistic selection on the X chromosome, permitting evolution toward a single sex-specific optimum. After multiple generations of selection, we found strong evidence that body size and development time had moved toward a female-specific optimum, whereas reproductive fitness and locomotion activity remained unchanged. The changes in body size and development time are consistent with previous results, and suggest that the X chromosome is enriched for sexually antagonistic genetic variation controlling these particular traits. The lack of change in reproductive fitness and locomotion activity could be due to a number of mutually nonexclusive explanations, including a lack of sexually antagonistic variance on the X chromosome for those traits or confounding effects of the use of the balancer chromosome. This study is the first to employ female-genome-limited selection and adds to the understanding of the complexity of sexually antagonistic genetic variation.
(Less)
- author
- Lund-Hansen, Katrine K.
LU
; Abbott, Jessica K.
LU
and Morrow, Edward H.
- organization
- publishing date
- 2020-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Drosophila melanogaster, experimental evolution, intralocus sexual conflict, sex chromosomes, sexual antagonism
- in
- Evolution
- volume
- 74
- issue
- 12
- pages
- 11 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85085885011
- pmid:32438467
- ISSN
- 0014-3820
- DOI
- 10.1111/evo.14021
- language
- English
- LU publication?
- yes
- id
- e4a2a2f4-931e-4b88-b12a-2285979cacb4
- date added to LUP
- 2020-07-03 11:50:17
- date last changed
- 2024-06-26 18:15:38
@article{e4a2a2f4-931e-4b88-b12a-2285979cacb4,
abstract = {{<p>A handful of studies have investigated sexually antagonistic constraints on achieving sex-specific fitness optima, although exclusively through male-genome-limited evolution experiments. In this article, we established a female-limited X chromosome evolution experiment, where we used an X chromosome balancer to enforce the inheritance of the X through the matriline, thus removing exposure to male selective constraints. This approach eliminates the effects of sexually antagonistic selection on the X chromosome, permitting evolution toward a single sex-specific optimum. After multiple generations of selection, we found strong evidence that body size and development time had moved toward a female-specific optimum, whereas reproductive fitness and locomotion activity remained unchanged. The changes in body size and development time are consistent with previous results, and suggest that the X chromosome is enriched for sexually antagonistic genetic variation controlling these particular traits. The lack of change in reproductive fitness and locomotion activity could be due to a number of mutually nonexclusive explanations, including a lack of sexually antagonistic variance on the X chromosome for those traits or confounding effects of the use of the balancer chromosome. This study is the first to employ female-genome-limited selection and adds to the understanding of the complexity of sexually antagonistic genetic variation.</p>}},
author = {{Lund-Hansen, Katrine K. and Abbott, Jessica K. and Morrow, Edward H.}},
issn = {{0014-3820}},
keywords = {{Drosophila melanogaster; experimental evolution; intralocus sexual conflict; sex chromosomes; sexual antagonism}},
language = {{eng}},
number = {{12}},
pages = {{2703--2713}},
publisher = {{Wiley-Blackwell}},
series = {{Evolution}},
title = {{Feminization of complex traits in Drosophila melanogaster via female-limited X chromosome evolution}},
url = {{http://dx.doi.org/10.1111/evo.14021}},
doi = {{10.1111/evo.14021}},
volume = {{74}},
year = {{2020}},
}