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Synthesis of α-Keto Amides by a Pyrrolidine/TEMPO-Mediated Oxidation of α-Keto Amines

Yu, Lu LU and Somfai, Peter LU (2016) In Synlett 27(18). p.2587-2590
Abstract

A mild procedure has been developed for the synthesis of α-keto amides by α-oxidation of the corresponding α-keto amines mediated by pyrrolidine and TEMPO. The method can also be applied to the synthesis of α-keto thioamides and α-keto amidines.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
amides, amines, catalysis, ketones, oxidation, thioamides
in
Synlett
volume
27
issue
18
pages
4 pages
publisher
Georg Thieme Verlag
external identifiers
  • scopus:84983020532
  • wos:000387254900012
ISSN
0936-5214
DOI
10.1055/s-0035-1562541
language
English
LU publication?
yes
id
e506a515-3f20-46d0-b7a5-acfbd0b7aa4d
date added to LUP
2016-11-18 15:29:39
date last changed
2017-01-01 08:40:06
@article{e506a515-3f20-46d0-b7a5-acfbd0b7aa4d,
  abstract     = {<p>A mild procedure has been developed for the synthesis of α-keto amides by α-oxidation of the corresponding α-keto amines mediated by pyrrolidine and TEMPO. The method can also be applied to the synthesis of α-keto thioamides and α-keto amidines.</p>},
  articleno    = {st-2016-b0315-l},
  author       = {Yu, Lu and Somfai, Peter},
  issn         = {0936-5214},
  keyword      = {amides,amines,catalysis,ketones,oxidation,thioamides},
  language     = {eng},
  month        = {11},
  number       = {18},
  pages        = {2587--2590},
  publisher    = {Georg Thieme Verlag},
  series       = {Synlett},
  title        = {Synthesis of α-Keto Amides by a Pyrrolidine/TEMPO-Mediated Oxidation of α-Keto Amines},
  url          = {http://dx.doi.org/10.1055/s-0035-1562541},
  volume       = {27},
  year         = {2016},
}