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Respiratory adenovirus infections in immunocompetent and immunocompromised adult patients

Cederwall, S. LU and Påhlman, L. I. LU (2020) In Epidemiology and Infection 147.
Abstract

Adenovirus (AdV) can cause severe respiratory infections in children and immunocompromised patients, but less is known about severe AdV pneumonia in immunocompetent adults. In this retrospective study, we compared respiratory tract infections and pneumonia caused by AdV in immunocompromised and immunocompetent adult patients regarding clinical presentation and severity of infection. The results show that AdV can cause severe infections in both immunocompetent and immunocompromised patients, and the clinical presentation and need for hospitalisation, mechanical ventilation and antiviral treatment were equal in both groups. No underlying risk factors for severe AdV infection in healthy individuals were identified.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adenoviruses, respiratory infections
in
Epidemiology and Infection
volume
147
article number
e328
publisher
Cambridge University Press
external identifiers
  • pmid:31896387
  • scopus:85077433986
ISSN
0950-2688
DOI
10.1017/S0950268819002176
language
English
LU publication?
yes
id
e54ac12f-c337-4065-8aaa-72937597bbb8
date added to LUP
2020-01-21 17:17:54
date last changed
2020-01-22 07:50:39
@article{e54ac12f-c337-4065-8aaa-72937597bbb8,
  abstract     = {<p>Adenovirus (AdV) can cause severe respiratory infections in children and immunocompromised patients, but less is known about severe AdV pneumonia in immunocompetent adults. In this retrospective study, we compared respiratory tract infections and pneumonia caused by AdV in immunocompromised and immunocompetent adult patients regarding clinical presentation and severity of infection. The results show that AdV can cause severe infections in both immunocompetent and immunocompromised patients, and the clinical presentation and need for hospitalisation, mechanical ventilation and antiviral treatment were equal in both groups. No underlying risk factors for severe AdV infection in healthy individuals were identified.</p>},
  author       = {Cederwall, S. and Påhlman, L. I.},
  issn         = {0950-2688},
  language     = {eng},
  month        = {01},
  publisher    = {Cambridge University Press},
  series       = {Epidemiology and Infection},
  title        = {Respiratory adenovirus infections in immunocompetent and immunocompromised adult patients},
  url          = {http://dx.doi.org/10.1017/S0950268819002176},
  doi          = {10.1017/S0950268819002176},
  volume       = {147},
  year         = {2020},
}