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Emerging strategies in 3D printed tissue models for in vitro biomedical research

Pless, Christian J. ; Radeke, Carmen ; Cakal, Selgin D. ; Kajtez, Janko LU orcid ; Pasqualini, Francesco S. and Lind, Johan U. (2022) p.207-246
Abstract

3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.

Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Embedded printing, Extracellular matrix, Multimaterial printing, Organs-on-chips, Stem cell biology, Tissue engineering, Tissue models
host publication
Bioprinting : From Multidisciplinary Design to Emerging Opportunities - From Multidisciplinary Design to Emerging Opportunities
pages
40 pages
publisher
Academic Press
external identifiers
  • scopus:85137565974
ISBN
9780323854313
9780323854306
DOI
10.1016/B978-0-323-85430-6.00007-8
language
English
LU publication?
yes
id
e57806a6-9a14-4f35-8ff5-4ebc7d911a00
date added to LUP
2022-12-02 12:32:28
date last changed
2024-04-18 09:02:36
@inbook{e57806a6-9a14-4f35-8ff5-4ebc7d911a00,
  abstract     = {{<p>3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.</p>}},
  author       = {{Pless, Christian J. and Radeke, Carmen and Cakal, Selgin D. and Kajtez, Janko and Pasqualini, Francesco S. and Lind, Johan U.}},
  booktitle    = {{Bioprinting : From Multidisciplinary Design to Emerging Opportunities}},
  isbn         = {{9780323854313}},
  keywords     = {{Embedded printing; Extracellular matrix; Multimaterial printing; Organs-on-chips; Stem cell biology; Tissue engineering; Tissue models}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{207--246}},
  publisher    = {{Academic Press}},
  title        = {{Emerging strategies in 3D printed tissue models for in vitro biomedical research}},
  url          = {{http://dx.doi.org/10.1016/B978-0-323-85430-6.00007-8}},
  doi          = {{10.1016/B978-0-323-85430-6.00007-8}},
  year         = {{2022}},
}